The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis

CA Roberts, AK Dickinson, LS Taams - Frontiers in immunology, 2015 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation
of the synovial lining (synovitis). The inflammation in the RA joint is associated with and …

Interleukin-23: a key cytokine in inflammatory diseases

E Duvallet, L Semerano, E Assier, G Falgarone… - Annals of …, 2011 - Taylor & Francis
Abstract Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, p19
and p40. The p40 subunit is shared with IL-12. IL-23 and IL-12 have different receptors and …

Proinflammatory cytokines (IL-1,-6,-8,-15,-17,-18,-23, TNF-α) single nucleotide polymorphisms in rheumatoid arthritis—a literature review

OM Koper-Lenkiewicz, K Sutkowska… - International Journal of …, 2022 - mdpi.com
Conducted studies highlight that a mixture of genetic and environmental factors is
responsible for rheumatoid arthritis (RA) development. This study aimed to analyze the …

The anti‐CD20 antibody rituximab reduces the Th17 cell response

FL van de Veerdonk, B Lauwerys… - Arthritis & …, 2011 - Wiley Online Library
Objective Rituximab has been shown to be successful in the treatment of rheumatoid arthritis
(RA), and this unexpected finding indicates that B cells have an important role in this …

Th17 Cells in Immunopathogenesis and treatment of rheumatoid arthritis

G Azizi, F Jadidi‐Niaragh… - International journal of …, 2013 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the
sequestration of various leukocyte subpopulations within both the developing pannus and …

Activation of Th17 cells in drug naïve, first episode schizophrenia

M Ding, X Song, J Zhao, J Gao, X Li, G Yang… - Progress in neuro …, 2014 - Elsevier
Objective The present study was to examine the role of pro-inflammatory T helper 17 (Th17)
cells in drug naïve, first episode schizophrenia. Method Patients with normal weight, drug …

Th17 cells: critical mediators of host responses to burn injury and sepsis

JL Rendon, MA Choudhry - Journal of leukocyte biology, 2012 - academic.oup.com
Review on Th17 cells in critical care settings, including burn injury and clinical sepsis, and
the potential therapeutic role of IL-22. Th cells have long been recognized as vital …

Increased interleukin 21 (IL-21) and IL-23 are associated with increased disease activity and with radiographic status in patients with early rheumatoid arthritis

TK Rasmussen, T Andersen, M Hvid… - The Journal of …, 2010 - jrheum.org
Objective. To investigate the levels of the T helper (Th) 17-related cytokines interleukin 17A
(IL-17A), IL-21, and IL-23 and their association with disease activity in rheumatoid arthritis …

Overexpression and selectively regulatory roles of IL‐23/IL‐17 axis in the lesions of oral lichen planus

R Lu, X Zeng, Q Han, M Lin, L Long… - Mediators of …, 2014 - Wiley Online Library
Interleukin‐(IL‐) 23/IL‐17 axis is a newly discovered proinflammatory signaling pathway and
has been implicated in the pathogenesis of many chronic inflammatory and immune …

Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population

B Yang, J Chen, Y Li, J Zhang, D Li, Z Huang, B Cai… - Human Immunology, 2012 - Elsevier
The aim of this study was to detect the association between 2 single nucleotide
polymorphisms (SNPs), rs2910164 G> C and rs3746444 T> C, in pre-miRNA (hsa-mir-146a …