Current and future trends in antibiotic therapy of acute bacterial skin and skin-structure infections
A Russo, E Concia, F Cristini, FG De Rosa… - Clinical Microbiology …, 2016 - Elsevier
In 2013 the US Food and Drug Administration (FDA) issued recommendations and guidance
on developing drugs for treatment of skin infection using a new definition of acute bacterial …
on developing drugs for treatment of skin infection using a new definition of acute bacterial …
Management of complicated skin and soft tissue infections with a special focus on the role of newer antibiotics
HN Leong, A Kurup, MY Tan, ALH Kwa… - Infection and drug …, 2018 - Taylor & Francis
Complicated skin and soft tissue infections (cSSTIs) represent the severe form of infectious
disease that involves deeper soft tissues. Involvement of methicillin-resistant …
disease that involves deeper soft tissues. Involvement of methicillin-resistant …
Omadacycline for acute bacterial skin and skin-structure infections
W O'Riordan, S Green, JS Overcash… - … England Journal of …, 2019 - Mass Medical Soc
Background Acute bacterial skin and skin-structure infections are associated with substantial
morbidity and health care costs. Omadacycline, an aminomethylcycline antibiotic that can be …
morbidity and health care costs. Omadacycline, an aminomethylcycline antibiotic that can be …
Expression of the Biofilm-Associated Genes in Methicillin-Resistant Staphylococcus aureus in Biofilm and Planktonic Conditions
B Kot, H Sytykiewicz, I Sprawka - International journal of molecular …, 2018 - mdpi.com
The role of genes that are essential for development of Staphylococcus aureus biofilm
during infection is not fully known. mRNA from two methicillin-resistant S. aureus strains that …
during infection is not fully known. mRNA from two methicillin-resistant S. aureus strains that …
Once-daily oral omadacycline versus twice-daily oral linezolid for acute bacterial skin and skin structure infections (OASIS-2): a phase 3, double-blind, multicentre …
W O'Riordan, C Cardenas, E Shin, A Sirbu… - The Lancet Infectious …, 2019 - thelancet.com
Background Pathogen resistance and safety concerns limit oral antibiotic options for the
treatment of acute bacterial skin and skin structure infections (ABSSSI). We aimed to …
treatment of acute bacterial skin and skin structure infections (ABSSSI). We aimed to …
A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft …
X Zhao, H Huang, H Yuan, Z Yuan… - Journal of Antimicrobial …, 2022 - academic.oup.com
Objectives Contezolid is a novel oxazolidinone antibacterial agent for managing infections
caused by aerobic and anaerobic Gram-positive bacteria including methicillin-resistant …
caused by aerobic and anaerobic Gram-positive bacteria including methicillin-resistant …
Role of extracellular DNA in dalbavancin activity against methicillin-resistant Staphylococcus aureus (MRSA) biofilms in patients with skin and soft tissue infections
F Sivori, I Cavallo, D Kovacs, M Guembe… - Microbiology …, 2022 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) has become the leading cause of skin
and soft tissue infections (SSTIs). Biofilm production further complicates patient treatment …
and soft tissue infections (SSTIs). Biofilm production further complicates patient treatment …
Host physiologic changes induced by influenza A virus lead to Staphylococcus aureus biofilm dispersion and transition from asymptomatic colonization to invasive …
RM Reddinger, NR Luke-Marshall, AP Hakansson… - MBio, 2016 - Am Soc Microbiol
Staphylococcus aureus is a ubiquitous opportunistic human pathogen and a major health
concern worldwide, causing a wide variety of diseases from mild skin infections to systemic …
concern worldwide, causing a wide variety of diseases from mild skin infections to systemic …
[HTML][HTML] Early clinical assessment of response to treatment of skin and soft-tissue infections: how can it help clinicians? Perspectives from Europe
D Nathwani, M Dryden, J Garau - International Journal of Antimicrobial …, 2016 - Elsevier
Skin and soft-tissue infections (SSTIs) are a common indication for antibiotic use in Europe
and are associated with considerable morbidity. Treatment of SSTIs, occasionally …
and are associated with considerable morbidity. Treatment of SSTIs, occasionally …
Hot topics in the diagnosis and management of skin and soft-tissue infections
Eighteen hot topics regarding the diagnosis and management of skin and soft-tissue
infections (SSTIs) were selected and reviewed by members of the SSTI Working Group of …
infections (SSTIs) were selected and reviewed by members of the SSTI Working Group of …