Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in
part can become irreversible to conventional therapies, defining the concept of airway …

Rhinovirus infections can cause wheezing illnesses in all age groups. In preschool children,
rhinovirus infections frequently initiate acute wheezing illnesses. Children who wheeze with …

Introduction Consensus definitions for clinical remission and super-response were recently
established for severe asthma. Benralizumab is an interleukin-5 (IL-5) receptor α-directed …

Rationale: Tezepelumab reduced exacerbations in patients with severe, uncontrolled
asthma across a range of baseline blood eosinophil counts and fractional exhaled nitric …

Five biological drugs are currently marketed for treatment of uncontrolled severe asthma.
They all block type 2 inflammatory pathways by targeting IgE (omalizumab), the IL-5 …

Background Patients with severe asthma may require maintenance oral corticosteroids
(mOCS) for disease control as well as systemic corticosteroid (SCS) bursts for clinically …

Das Management von Asthma hat sich in den letzten Jahrzehnten fundamental gewandelt.
Die vorliegende Leitlinie zur Diagnostik und Therapie von Asthma wurde für pneumologisch …

Systemic corticosteroids (SCS) are a highly effective treatment for acute exacerbations and
long-term symptom control in asthma. Long-term SCS use is highly prevalent across all …

Aim The International Severe Asthma Registry (ISAR; http://isaregistries. org/) uses
standardised variables to enable multi-country and adequately powered research in severe …

Abstract Background The ORBE II study aimed to describe the characteristics and clinical
outcomes of adult patients with severe eosinophilic asthma (SEA) treated with benralizumab …