Degeneracy, defined as the ability of structurally disparate elements to perform analogous
function, has largely been assessed from the perspective of maintaining robustness of …

Most neurons have large numbers of voltage-and time-dependent currents that contribute to
their electrical firing patterns. Because these currents are nonlinear, it can be difficult to …

Biological neurons show significant cell-to-cell variability but have the striking ability to
maintain their key firing properties in the face of unpredictable perturbations and stochastic …

In multipolar vertebrate neurons, action potentials (APs) initiate close to the soma, at the
axonal initial segment. Invertebrate neurons are typically unipolar with dendrites integrating …

Drosophila is an important model organism for investigating neural development, neural
morphology, neurophysiology, and neural correlates of behaviors. However, almost nothing …

Dendrites shape information flow in neurons. Yet, there is little consensus on the level of
spatial complexity at which they operate. Through carefully chosen parameter fits, solvable …

An open question within the Bienenstock-Cooper-Munro theory for synaptic modification
concerns the specific mechanism that is responsible for regulating the sliding modification …

Key points• Voltage‐gated ion channels (VGICs) play a critical role in determining how
neurons respond to oscillatory inputs at various frequencies. How do inactivating VGICs …

Computational models of rhythmic motor systems are valuable tools for the study of motor
pattern generation and control. Recent modeling advances, together with experimental …

Conductance-based neuron models are frequently employed to study the dynamics of
biological neural networks. For speed and ease of use, these models are often reduced in …