Overview of hepatitis B viral replication and genetic variability

S Tong, P Revill - Journal of hepatology, 2016 - Elsevier
Chronic infection with hepatitis B virus (HBV) greatly increases the risk for liver cirrhosis and
hepatocellular carcinoma (HCC). HBV isolates worldwide can be divided into ten genotypes …

How viral genetic variants and genotypes influence disease and treatment outcome of chronic hepatitis B. Time for an individualised approach?

N Rajoriya, C Combet, F Zoulim, HLA Janssen - Journal of hepatology, 2017 - Elsevier
Chronic hepatitis B virus (HBV) infection remains a global problem. Several HBV genotypes
exist with different biology and geographical prevalence. Whilst the future aim of HBV …

Ten millennia of hepatitis B virus evolution

A Kocher, L Papac, R Barquera, FM Key, MA Spyrou… - Science, 2021 - science.org
Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health
problem, but its past diversity and dispersal routes are largely unknown. We generated HBV …

[HTML][HTML] Hepatitis B virus taxonomy and hepatitis B virus genotypes

S Schaefer - World journal of gastroenterology: WJG, 2007 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) is a member of the hepadnavirus family. Hepadnaviruses can be
found in both mammals (orthohepadnaviruses) and birds (avihepadnaviruses). The genetic …

Hepatitis B virus genotypes

A Kramvis, M Kew, G François - Vaccine, 2005 - Elsevier
Eight genotypes of hepatitis B virus (A–H) are currently recognized, and subgenotypes have
recently been described in four of these genotypes (A, B, C and F). The genotypes show a …

New complex recombinant genotype of hepatitis B virus identified in Vietnam

TTT Huy, TT Ngoc, K Abe - Journal of virology, 2008 - Am Soc Microbiol
ABSTRACT A novel variant of hepatitis B virus was identified in Vietnam. This strain (HBV-
VH24) had a novel intergenotypic recombination between genotypes A, C, and G. VH24 …

The influence of hepatitis B virus genotype and subgenotype on the natural history of chronic hepatitis B

BJ McMahon - Hepatology international, 2009 - Springer
Background Chronic infection with hepatitis B virus (HBV) is associated with a high lifetime
risk of developing hepatocellular carcinoma (HCC) and cirrhosis of the liver. Purpose To …

[HTML][HTML] Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance

CMN Croagh, PV Desmond, SJ Bell - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Abstract The Hepatitis B Virus (HBV) has a worldwide distribution and is endemic in many
populations. It is constantly evolving and 10 genotypic strains have been identified with …

High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases

BF Chen, CJ Liu, GM Jow, PJ Chen, JH Kao, DS Chen - Gastroenterology, 2006 - Elsevier
Background & Aims: The interactions among pre-S deletion, precore (PC) mutation, and
basal core promoter (BCP) mutation in various stages of chronic hepatitis B virus (HBV) …

Classifying hepatitis B virus genotypes

Y Miyakawa, M Mizokami - Intervirology, 2003 - karger.com
In 1988, hepatitis B virus (HBV) was classified into four genotypes by a sequence
divergence in the entire genome exceeding 8%, and designated by capital letters of the …