Presenting authoritative and engaging articles on all aspects of drug development, dosage,
manufacturing, and regulation, this Third Edition enables the pharmaceutical specialist and …

Mini-tablets are solid dosage forms with increasing interest for pharmaceutical industry due
to clinical and biopharmaceutical benefits. But technological aspects on mini-tableting are …

Numerous studies elucidated material behavior based on compression analyses. Especially
compressibility, compactibility and tabletability were in the focus of these investigations. In …

Adhesion problems are usually not identified until prolonged compression runs are studied
near the end of the drug development process. During tablet manufacturing, adhesion …

The deformation mechanism of pharmaceutical powders, used in formulating directly
compressed matrix tablets, affects the characteristics of the formed tablets. Three polymers …

The deformation behavior of particles under pressure dominates the mechanical properties
of solid dosage forms. In this study, the in situ 3D deformation of two polymorphs (I and II) of …

A compaction calorimeter, previously described (DeCrosta, MT, Schwartz, JB, Wigent, JB,
Marshall, K., 2000. Thermodynamic analysis of compact formation; compaction, unloading …

The influence of binder type and process parameters on the compression properties and
microbial survival in diclofenac tablet formulations were studied using a novel gum from …

A avaliação do comportamento de complexos farmacêuticos quando submetidos a
compressão tem sido como objetivo de diversos estudos tecnológicos. As principais …

This article is designed to facilitate the understanding of the general principles of tablet
press instrumentation and the benefits thereof by the formulators, process engineers …