Regulators in the apoptotic pathway during spermatogenesis: killers or guards?

YR Xu, HS Dong, WX Yang - Gene, 2016 - Elsevier
Apoptosis occurs at any time in the ontogeny of the testis, especially during the first wave of
spermatogenesis. However, the exact mechanisms by which homeostasis of apoptosis and …

Oestrogens as apoptosis regulators in mammalian testis: angels or devils?

S Correia, HJ Cardoso, JE Cavaco… - Expert reviews in …, 2015 - cambridge.org
In the mammalian testis, spermatogenesis is a highly coordinated process of germ cell
development, which ends with the release of 'mature'spermatozoa. The fine regulation of …

[HTML][HTML] Genome changes due to artificial selection in US Holstein cattle

L Ma, TS Sonstegard, JB Cole, CP VanTassell… - BMC genomics, 2019 - Springer
Background The availability of a unique unselected Holstein line since 1964 provided a
direct comparison between selected and unselected Holstein genomes whereas large …

[HTML][HTML] In vitro cultured human Sertoli cells secrete high amounts of acetate that is stimulated by 17β-estradiol and suppressed by insulin deprivation

MG Alves, S Socorro, J Silva, A Barros, M Sousa… - … et Biophysica Acta (BBA …, 2012 - Elsevier
BACKGROUND: Several important functions for a successful spermatogenesis are
dependent on Sertoli cells (SCs). Besides their unique characteristics as support cells, they …

Differential roles of estrogen receptors, ESR1 and ESR2, in adult rat spermatogenesis

K Dumasia, A Kumar, S Deshpande… - Molecular and cellular …, 2016 - Elsevier
Estrogens, through their receptors, play an important role in regulation of spermatogenesis.
However, the precise role of the estrogen receptors (ESR1 and ESR2) has been difficult to …

[HTML][HTML] Estrogenic regulation of testicular expression of stem cell factor and c-kit: implications in germ cell survival and male fertility

S Correia, MR Alves, JE Cavaco, PF Oliveira… - Fertility and sterility, 2014 - Elsevier
Objective To study the effect of estrogens regulating the testicular expression of stem cell
factor (SCF) and c-kit. Design Experimental study. Setting University research center. Animal …

Regulation of apoptotic signaling pathways by 5α-dihydrotestosterone and 17β-estradiol in immature rat Sertoli cells

VL Simoes, MG Alves, AD Martins, TR Dias… - The Journal of steroid …, 2013 - Elsevier
Apoptosis is an important regulatory event in testicular homeostasis and optimization of
sperm production. Sertoli cells (SCs) form the blood–testis barrier creating a special …

Regucalcin, a calcium-binding protein with a role in male reproduction?

SS Laurentino, S Correia, JE Cavaco… - Molecular human …, 2012 - academic.oup.com
Regucalcin (RGN) is a calcium (Ca2+)-binding protein which plays an important role in the
regulation of Ca2+ homeostasis and has been shown to catalyse an important step in l …

Single-step genome-wide association study and candidate genes networks affecting reproductive traits in Iranian Holstein cattle

A Mohammadi, S Alijani, SA Rafat… - Livestock Science, 2022 - Elsevier
The process of reproductive in domestic livestock is one of the most important challenges of
animal husbandry. Fertility is an important trait that contributes to herd profitability, and it can …

Expression pattern of G protein-coupled receptor 30 in human seminiferous tubular cells

PF Oliveira, MG Alves, AD Martins, S Correia… - General and …, 2014 - Elsevier
The role of estrogens in male reproductive physiology has been intensively studied over the
last few years. Yet, the involvement of their specific receptors has long been a matter of …