[HTML][HTML] cgNA+ web: A visual interface to the cgNA+ sequence-dependent statistical mechanics model of double-stranded nucleic acids

R Sharma, AS Patelli, L De Bruin… - Journal Of Molecular …, 2023 - Elsevier
The sequence-dependent statistical mechanics of double-stranded nucleic acid, or dsNA, is
believed to be essential in its biological functions. In turn, the equilibrium statistical …

Systematic Coarse-Graining of Sequence-Dependent Structure and Elasticity of Double-Stranded DNA

E Skoruppa, H Schiessel - arXiv preprint arXiv:2409.05510, 2024 - arxiv.org
Coarse-grained models have played an important role in the study of the behavior of DNA at
length scales beyond a few hundred base pairs. Traditionally, these models have relied on …

Landscapes of DNA mechanics and Genomes

TA Zwahlen - 2023 - infoscience.epfl.ch
The local physical properties-such as shape and flexibility-of the DNA double-helix is today
widely believed to be influenced by nucleic acid sequence in a non-trivial way. Furthermore …

Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications

R Giniūnaitė, R Sharma, JH Maddocks, S Kriaucionis… - bioRxiv, 2024 - biorxiv.org
The majority of vertebrate promoters have a distinct DNA composition, known as a CpG
island. Cytosine methylation in promoter CpG islands is associated with a substantial …

[PDF][PDF] Patelli

R Sharma - S., Bruin, L. de, & Maddocks,. H, 2023 - scholarlypublications …
The sequence-dependent statistical mechanics of double-stranded nucleic acid, or dsNA, is
believed to be essential in its biological functions. In turn, the equilibrium statistical …

Temperature-dependent elasticity of DNA, RNA, and hybrid double helices

H Dohnalová, E Matoušková, F Lankaš - Biophysical Journal, 2024 - cell.com
Nucleic acid double helices in their DNA, RNA, and DNA-RNA hybrid form play a
fundamental role in biology and are main building blocks of artificial nanostructures, but how …