[HTML][HTML] Animal models of NAFLD from a hepatologist's point of view
D Jahn, S Kircher, HM Hermanns, A Geier - Biochimica et Biophysica Acta …, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disorder closely linked to obesity,
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …
Mouse models in non‐alcoholic fatty liver disease and steatohepatitis research
QM Anstee, RD Goldin - International journal of experimental …, 2006 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) represents a histological spectrum of liver disease
associated with obesity, diabetes and insulin resistance that extends from isolated steatosis …
associated with obesity, diabetes and insulin resistance that extends from isolated steatosis …
[HTML][HTML] A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation
Background: Bacterial endotoxin is a potently inflammatory antigen that is abundant in the
human gut. Endotoxin circulates at low concentrations in the blood of all healthy individuals …
human gut. Endotoxin circulates at low concentrations in the blood of all healthy individuals …
[PDF][PDF] Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
K Wouters, PJ van Gorp, V Bieghs, MJ Gijbels… - …, 2008 - Wiley Online Library
Nonalcoholic steatohepatitis (NASH) involves liver lipid accumulation (steatosis) combined
with hepatic inflammation. The transition towards hepatic inflammation represents a key step …
with hepatic inflammation. The transition towards hepatic inflammation represents a key step …
[HTML][HTML] Supplementation with calcium+ vitamin D enhances the beneficial effect of weight loss on plasma lipid and lipoprotein concentrations
GC Major, F Alarie, J Doré, S Phouttama… - The American journal of …, 2007 - Elsevier
Background: Adequate calcium intake can have a favorable effect on some metabolic
variables. Objective: The objective of the study was to determine the effects of daily calcium …
variables. Objective: The objective of the study was to determine the effects of daily calcium …
[HTML][HTML] Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH
M Itoh, A Tamura, S Kanai, M Tanaka… - Journal of Experimental …, 2023 - rupress.org
Accumulation of lipotoxic lipids, such as free cholesterol, induces hepatocyte death and
subsequent inflammation and fibrosis in the pathogenesis of nonalcoholic steatohepatitis …
subsequent inflammation and fibrosis in the pathogenesis of nonalcoholic steatohepatitis …
[HTML][HTML] LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
Background & Aims Non-alcoholic steatohepatitis (NASH) involves steatosis combined with
inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular …
inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular …
Surfactant lipids at the host–environment interface. Metabolic sensors, suppressors, and effectors of inflammatory lung disease
MB Fessler, RS Summer - American Journal of Respiratory Cell and …, 2016 - atsjournals.org
The lipid composition of pulmonary surfactant is unlike that of any other body fluid. This
extracellular lipid reservoir is also uniquely susceptible by virtue of its direct and continuous …
extracellular lipid reservoir is also uniquely susceptible by virtue of its direct and continuous …
Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet
Nonalcoholic steatohepatitis (NASH) comprises dysregulation of lipid metabolism and
inflammation. Identification of the various genetic and environmental susceptibility factors for …
inflammation. Identification of the various genetic and environmental susceptibility factors for …
Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice
V Bieghs, K Wouters, PJ Van Gorp, MJJ Gijbels… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is a disorder that consists of
steatosis and hepatic inflammation. It is not known why only some people with steatosis …
steatosis and hepatic inflammation. It is not known why only some people with steatosis …