MicroRNAs (miRNAs) are short, noncoding RNAs that posttranscriptionally regulate gene
expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of …

Recent progress in high throughput sequencing and bioinformatic analysis and other
biochemical methods have fuelled our appreciation for the important role of microRNAs …

Context Polycystic ovary syndrome (PCOS), a complex and heterogeneous endocrine
condition, is characterized by polycystic ovaries, hyperandrogenism, insulin resistance and …

STUDY QUESTION What is the expression pattern of microRNAs (miRNAs) in human
cumulus–oocyte complexes (COCs)? SUMMARY ANSWER Several miRNAs are enriched …

The genetic regulation of female fertility (follicular development, oocyte maturation and early
preimplantation embryo development) involves the spatio-temporal regulation of those …

Several different miRNAs have been proposed to regulate ovarian follicle function; however,
very limited information exists on the spatiotemporal patterns of miRNA expression during …

We sought to investigate whether miR-378 plays a role in cumulus cells and whether the
manipulation of miRNA levels in cumulus cells influences oocyte maturation in vitro …

The mammalian ovary is a dynamic organ. The coordination of follicle recruitment, selection,
and ovulation and the timely development and regression of the corpus luteum are essential …

Background MicroRNAs have been suggested to play important roles in the regulation of
gene expression in various biological processes. To investigate the function of miRNAs in …

Circulating or “extracellular” microRNAs (miRNAs) detected in biological fluids, could be
used as potential diagnostic and prognostic biomarkers of several disease, such as cancer …