Owing to their ability to efficiently generate ATP required to sustain normal cell function,
mitochondria are often considered the 'powerhouses of the cell'. However, our …

Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …

Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

Dynamin superfamily proteins (DSPs) mediate membrane fission and fusion necessary for
endocytosis, organelle biogenesis and maintenance, as well as for bacterial cytokinesis …

Several species of unicellular eukaryotic algae exhibit relatively simple genomic and cellular
architecture. Laboratory cultures of these algae grow faster than plants and often provide …

The diverse GTPases of the dynamin superfamily play various roles in the cell, as
exemplified by the dynamin-related proteins (DRPs) Mgm1 and Opa1, which remodel the …

Membrane proteins mediate a number of cellular functions and are associated with several
diseases and also play a crucial role in pathogenicity. Due to their importance in cellular …

Mitochondrial fission is a critical cellular event to maintain organelle function. This multistep
process is initiated by the enhanced recruitment and oligomerization of dynamin-related …

Dynamin‐related proteins are multidomain, mechanochemical GTPases that self‐assemble
and orchestrate a wide array of cellular processes. Over the past decade, structural insights …

Mitochondria and peroxisomes proliferate by division. During division, a part of their
membrane is pinched off by constriction of the ring-shaped mitochondrial division (MD) and …