Structural and functional diversity of type IV secretion systems

TRD Costa, JB Patkowski, K Macé, PJ Christie… - Nature Reviews …, 2024 - nature.com
Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

[HTML][HTML] Plasmid transfer by conjugation in Gram-negative bacteria: from the cellular to the community level

C Virolle, K Goldlust, S Djermoun, S Bigot, C Lesterlin - Genes, 2020 - mdpi.com
Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

TRD Costa, C Felisberto-Rodrigues, A Meir… - Nature Reviews …, 2015 - nature.com
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …

Type IV secretion systems: advances in structure, function, and activation

TRD Costa, L Harb, P Khara, L Zeng, B Hu… - Molecular …, 2021 - Wiley Online Library
Bacterial type IV secretion systems (T4SSs) are a functionally diverse translocation
superfamily. They consist mainly of two large subfamilies:(i) conjugation systems that …

Type IV secretion in Gram‐negative and Gram‐positive bacteria

E Grohmann, PJ Christie, G Waksman… - Molecular …, 2018 - Wiley Online Library
Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

[HTML][HTML] Molecular architecture of bacterial type IV secretion systems

MJ Sheedlo, MD Ohi, DB Lacy, TL Cover - PLoS pathogens, 2022 - journals.plos.org
Bacterial type IV secretion systems (T4SSs) are a versatile group of nanomachines that can
horizontally transfer DNA through conjugation and deliver effector proteins into a wide range …

Mobile genetic elements: the agents of open source evolution

LS Frost, R Leplae, AO Summers… - Nature Reviews …, 2005 - nature.com
Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of
DNA sequences in prokaryotic chromosomes that seem to have originated from other …

Biological diversity of prokaryotic type IV secretion systems

CE Alvarez-Martinez, PJ Christie - Microbiology and Molecular …, 2009 - Am Soc Microbiol
Type IV secretion systems (T4SS) translocate DNA and protein substrates across prokaryotic
cell envelopes generally by a mechanism requiring direct contact with a target cell. Three …

Structure and mechanism of helicases and nucleic acid translocases

MR Singleton, MS Dillingham, DB Wigley - Annu. Rev. Biochem., 2007 - annualreviews.org
Helicases and translocases are a ubiquitous, highly diverse group of proteins that perform
an extraordinary variety of functions in cells. Consequently, this review sets out to define a …

Variable effects of oxytetracycline on antibiotic resistance gene abundance and the bacterial community during aerobic composting of cow manure

X Qian, W Sun, J Gu, XJ Wang, JJ Sun, YN Yin… - Journal of hazardous …, 2016 - Elsevier
Livestock manure is often subjected to aerobic composting but little is known about the
variation in antibiotic resistance genes (ARGs) during the composting process under …