Exploring Klebsiella pneumoniae capsule polysaccharide proteins to design multiepitope subunit vaccine to fight against pneumonia

J Dey, SR Mahapatra, S Lata, S Patro… - Expert Review of …, 2022 - Taylor & Francis
Background Klebsiella pneumoniae is an emerging human pathogen causing neonatal lung
disease, catheter-associated infections, and nosocomial outbreaks with high fatality rates …

Recent approaches for downplaying antibiotic resistance: molecular mechanisms

S Ahmed, MZ Ahmed, S Rafique… - BioMed Research …, 2023 - Wiley Online Library
Antimicrobial resistance (AMR) is a ubiquitous public health menace. AMR emergence
causes complications in treating infections contributing to an upsurge in the mortality rate …

Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium

J Dey, SR Mahapatra, TK Raj, T Kaur, P Jain, A Tiwari… - Gut Pathogens, 2022 - Springer
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe
public health complications in humans. There are currently no licensed treatments or …

Immunoinformatics-guided designing of epitope-based subunit vaccine from Pilus assembly protein of Acinetobacter baumannii bacteria

SR Mahapatra, J Dey, A Jaiswal, R Roy, N Misra… - Journal of …, 2022 - Elsevier
Acinetobacter baumannii, a prominent pathogen responsible for chronic infections in the
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …

Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches

J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …

Molecular Characterization and Designing of a Novel Multiepitope Vaccine Construct Against Pseudomonas aeruginosa

J Dey, SR Mahapatra, S Patnaik, S Lata… - International Journal of …, 2022 - Springer
Pseudomonas aeruginosa, an ESKAPE pathogen causes many fatal clinical diseases in
humans across the globe. Despite an increase in clinical instances of Pseudomonas …

Designing a Next-Generation Multiepitope-Based Vaccine against Staphylococcus aureus Using Reverse Vaccinology Approaches

SR Mahapatra, J Dey, TK Raj, N Misra, M Suar - Pathogens, 2023 - mdpi.com
Staphylococcus aureus is a human bacterial pathogen that can cause a wide range of
symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S …

Genome-based identification and comparative analysis of enzymes for carotenoid biosynthesis in microalgae

PK Narang, J Dey, SR Mahapatra, R Roy… - World Journal of …, 2022 - Springer
Microalgae are potential feedstocks for the commercial production of carotenoids, however,
the metabolic pathways for carotenoid biosynthesis across algal lineage are largely …

An integrative reverse vaccinology, immunoinformatic, docking and simulation approaches towards designing of multi-epitopes based vaccine against monkeypox …

A Ullah, FA Shahid, MU Haq… - Journal of …, 2023 - Taylor & Francis
Monkeypox is a viral zoonotic disease that is caused by the monkeypox virus (MPXV) and is
mainly transmitted to human through close contact with an infected person, animal, or …

Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach

S Gul, S Ahmad, A Ullah, S Ismail, M Khurram… - Vaccines, 2022 - mdpi.com
Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over
some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to …