[HTML][HTML] Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
[HTML][HTML] Malaria: progress, perils, and prospects for eradication
There are still approximately 500 million cases of malaria and 1 million deaths from malaria
each year. Yet recently, malaria incidence has been dramatically reduced in some parts of …
each year. Yet recently, malaria incidence has been dramatically reduced in some parts of …
Microbial predators form a new supergroup of eukaryotes
DV Tikhonenkov, KV Mikhailov, RMR Gawryluk… - Nature, 2022 - nature.com
Molecular phylogenetics of microbial eukaryotes has reshaped the tree of life by
establishing broad taxonomic divisions, termed supergroups, that supersede the traditional …
establishing broad taxonomic divisions, termed supergroups, that supersede the traditional …
Role of host cell traversal by the malaria sporozoite during liver infection
J Tavares, P Formaglio, S Thiberge… - Journal of experimental …, 2013 - rupress.org
Malaria infection starts when the sporozoite stage of the Plasmodium parasite is injected into
the skin by a mosquito. Sporozoites are known to traverse host cells before finally invading a …
the skin by a mosquito. Sporozoites are known to traverse host cells before finally invading a …
[HTML][HTML] The silent path to thousands of merozoites: the Plasmodium liver stage
Plasmodium sporozoites are deposited in the skin of their vertebrate hosts through the bite
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
PD Crompton, MA Kayala, B Traore… - Proceedings of the …, 2010 - National Acad Sciences
Abs are central to malaria immunity, which is only acquired after years of exposure to
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …
Malaria parasite development in the mosquito and infection of the mammalian host
ASI Aly, AM Vaughan, SHI Kappe - Annual review of …, 2009 - annualreviews.org
Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …
[HTML][HTML] Liver immunology
The liver is the largest organ in the body and is generally regarded by non-immunologists as
not having lymphoid function. However, such is far from accurate. This review highlights the …
not having lymphoid function. However, such is far from accurate. This review highlights the …
Challenges and strategies for developing efficacious and long-lasting malaria vaccines
Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …
challenges remain for achieving highly efficacious and durable vaccines against …
[HTML][HTML] Looking under the skin: the first steps in malarial infection and immunity
Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …