Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Pathogenesis of Proteus mirabilis Infection

CE Armbruster, HLT Mobley, MM Pearson - EcoSal Plus, 2018 - Am Soc Microbiol
Proteus mirabilis, a Gram-negative rod-shaped bacterium most noted for its swarming
motility and urease activity, frequently causes catheter-associated urinary tract infections …

Escherichia coli: an old friend with new tidings

J Vila, E Sáez-López, JR Johnson… - FEMS microbiology …, 2016 - academic.oup.com
Escherichia coli is one of the most-studied microorganisms worldwide but its characteristics
are continually changing. Extraintestinal E. coli infections, such as urinary tract infections …

Recurrent urinary tract infection: a mystery in search of better model systems

BO Murray, C Flores, C Williams… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are among the most common infectious diseases worldwide
but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant …

Current murine models of sepsis

AJ Lewis, CW Seymour, MR Rosengart - Surgical infections, 2016 - liebertpub.com
Sepsis is a common clinical entity causing thousands of deaths and costing billions of
healthcare dollars annually in the US alone [1–4]. Further, sepsis and septic shock represent …

Role of Uropathogenic Escherichia coli Virulence Factors in Development of Urinary Tract Infection and Kidney Damage

J Bien, O Sokolova, P Bozko - International journal of …, 2012 - Wiley Online Library
Uropathogenic Escherichia coli (UPEC) is a causative agent in the vast majority of urinary
tract infections (UTIs), including cystitis and pyelonephritis, and infectious complications …

Virulence factors in Escherichia coli urinary tract infection

JR Johnson - Clinical microbiology reviews, 1991 - Am Soc Microbiol
Uropathogenic strains of Escherichia coli are characterized by the expression of distinctive
bacterial properties, products, or structures referred to as virulence factors because they …

Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis

SM Jacobsen, DJ Stickler, HLT Mobley… - Clinical microbiology …, 2008 - Am Soc Microbiol
Catheter-associated urinary tract infections (CAUTIs) represent the most common type of
nosocomial infection and are a major health concern due to the complications and frequent …

Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

TJ Hannan, M Totsika, KJ Mansfield… - FEMS microbiology …, 2012 - academic.oup.com
Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder

K Shin, J Lee, N Guo, J Kim, A Lim, L Qu, IU Mysorekar… - Nature, 2011 - nature.com
Epithelial integrity in metazoan organs is maintained through the regulated proliferation and
differentiation of organ-specific stem and progenitor cells. Although the epithelia of organs …