[HTML][HTML] Traumatic brain injury: mechanisms of glial response

RG Mira, M Lira, W Cerpa - Frontiers in physiology, 2021 - frontiersin.org
Traumatic brain injury (TBI) is a heterogeneous disorder that involves brain damage due to
external forces. TBI is the main factor of death and morbidity in young males with a high …

Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities

Y Xiong, A Mahmood, M Chopp - Chinese Journal of Traumatology, 2018 - mednexus.org
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective …

JK Yue, EL Yuh, FK Korley, EA Winkler, X Sun… - The Lancet …, 2019 - thelancet.com
Background After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …

Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy

BD Semple, A Zamani, G Rayner, SR Shultz… - Neurobiology of …, 2019 - Elsevier
Survivors of traumatic brain injury (TBI) often develop chronic neurological, neurocognitive,
psychological, and psychosocial deficits that can have a profound impact on an individual's …

[HTML][HTML] Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes

X Xu, M Cowan, F Beraldo, A Schranz… - Acta neuropathologica …, 2021 - Springer
We have previously reported long-term changes in the brains of non-concussed varsity
rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) …

Aberrant ER stress induced neuronal-IFNβ elicits white matter injury due to microglial activation and T-cell infiltration after TBI

T Sen, P Saha, R Gupta, LM Foley, T Jiang… - Journal of …, 2020 - Soc Neuroscience
Persistent endoplasmic reticulum (ER) stress in neurons is associated with activation of
inflammatory cells and subsequent neuroinflammation following traumatic brain injury (TBI); …

[HTML][HTML] Age matters: Microbiome depletion prior to repeat mild traumatic brain injury differentially alters microbial composition and function in adolescent and adult …

M Sgro, G Iacono, GR Yamakawa, ZN Kodila… - Plos one, 2022 - journals.plos.org
Dysregulation of the gut microbiome has been shown to perpetuate neuroinflammation, alter
intestinal permeability, and modify repetitive mild traumatic brain injury (RmTBI)-induced …

Behavioral comorbidities of epilepsy and neuroinflammation: Evidence from experimental and clinical studies

EM Suleymanova - Epilepsy & Behavior, 2021 - Elsevier
Currently, a significant amount of data is accumulated showing that neuroinflammation is
one of the key processes in the development of brain pathology in trauma …

[HTML][HTML] An integrated perspective linking physiological and psychological consequences of mild traumatic brain injury

HJ van der Horn, ML Out, ME de Koning, AR Mayer… - Journal of …, 2020 - Springer
Despite the often seemingly innocuous nature of a mild traumatic brain injury (mTBI), its
consequences can be devastating, comprising debilitating symptoms that interfere with daily …

[HTML][HTML] Amyloid PET across the cognitive spectrum in former professional and college American football players: findings from the DIAGNOSE CTE Research Project

RA Stern, D Trujillo-Rodriguez, Y Tripodis… - Alzheimer's Research & …, 2023 - Springer
Background Exposure to repetitive head impacts (RHI) in American football players can lead
to cognitive impairment and dementia due to neurodegenerative disease, particularly …