Adamantane derivatives: Pharmacological and toxicological properties
AA Spasov, TV Khamidova, LI Bugaeva… - Pharmaceutical …, 2000 - Springer
Original papers describing the biological properties of adamantane-containing drugs
reported on the antiviral activity of 1-aminoadamantane [1]. Presently, the amino derivatives …
reported on the antiviral activity of 1-aminoadamantane [1]. Presently, the amino derivatives …
Interactions of the antiviral and antiparkinson agent amantadine with lipid membranes and human erythrocytes
M Suwalsky, M Jemiola-Rzeminska, M Altamirano… - Biophysical …, 2015 - Elsevier
Aimed to better understand the molecular mechanisms of its interactions with cell
membranes, human erythrocyte and molecular models of the red cell membrane were …
membranes, human erythrocyte and molecular models of the red cell membrane were …
The influence of the antiviral drugs amantadine and rimantadine on erythrocyte and platelet membranes and its comparison with that of tetracaine
E Donath, A Herrmann, WT Coakley, T Groth… - Biochemical …, 1987 - Elsevier
The influence of the antivirus drugs amantadine and rimantadine and of the anionic
analogue 1-adamantane-carboxylic acid on a range of properties of human erythrocyte …
analogue 1-adamantane-carboxylic acid on a range of properties of human erythrocyte …
Functional characterization of p7 viroporin from hepatitis C virus produced in a cell-free expression system
T Soranzo, S Cortès, F Gilde, M Kreir, C Picart… - Protein expression and …, 2016 - Elsevier
Using a cell-free expression system we produced the p7 viroporin embedded into a lipid
bilayer in a single-step manner. The protein quality was assessed using different methods …
bilayer in a single-step manner. The protein quality was assessed using different methods …
In vitro and in vivo growth inhibition of cancer cells by adamantylmaleimide derivatives
JJ Wang, YT Chern, TY Liu, CW Chi - Anti-cancer drug design, 1998 - ingentaconnect.com
We have previously found that adamantylmaleimide derivatives inhibited the growth of
several cancer cell lines In vitro. In this study we examined the effect of adamantylmaleimide …
several cancer cell lines In vitro. In this study we examined the effect of adamantylmaleimide …
Dimethyladamantylmaleimide-induced in vitro and in vivo growth inhibition of human colon cancer Colo205 cells
Abstract The effect of N-1-(3, 5-dimethyladamantyl) maleimide (DMAMI) on the growth of
Colo205 human colon cancer cells was examined both in vitro and in vivo. Flow cytometry …
Colo205 human colon cancer cells was examined both in vitro and in vivo. Flow cytometry …
Induction of growth inhibition and G1 arrest in human cancer cell lines by relatively low-toxic diamantane derivatives
JJ Wang, KT Huang, YT Chern - Anti-cancer drugs, 2004 - journals.lww.com
We describe the discovery of a novel series of antitumor diamantane derivatives which
induces G 1 arrest in Colo 205 cells. Eight diamantane derivatives were screened for their …
induces G 1 arrest in Colo 205 cells. Eight diamantane derivatives were screened for their …
The antiviral drug amantadine has a direct inhibitory effect on T-lymphocytes
C Clark, MM Woodson, VB Winge, HT Nagasawa - Immunopharmacology, 1989 - Elsevier
We investigated the effect of the antiviral drug amantadine (AmTd) on polyclonal activation
of thymic-dependent (T) and thymic-independent (B) lymphocytes from normal mice. In the …
of thymic-dependent (T) and thymic-independent (B) lymphocytes from normal mice. In the …
Inhibition of lymphocyte proliferation by amantadine and its isomer, 2-aminoadamantane; impact on Lyt-2+ T cells while sparing L3T4+ cells
C Clark, MM Woodson, HT Nagasawa - Immunopharmacology, 1991 - Elsevier
The present in vitro investigations on amantadine (AmTd) and its isomer 2-
aminoadamantane (2-NH 2-Adam), and the corresponding analogs, 1-nitroadamantane (1 …
aminoadamantane (2-NH 2-Adam), and the corresponding analogs, 1-nitroadamantane (1 …
In vitro and in vivo growth inhibition and G1 arrest in human cancer cell lines by diaminophenyladamantane derivatives
JJ Wang, YC Chen, CW Chi, KT Huang… - Anti-cancer …, 2004 - journals.lww.com
We describe the discovery of a novel series of anticancer adamantane derivatives which
induce G 1 arrest in Colo 205 and HT 29 colon cancer cells. Seven adamantane derivatives …
induce G 1 arrest in Colo 205 and HT 29 colon cancer cells. Seven adamantane derivatives …