Cultivating meat from stem cells rather than by raising animals is a promising solution to
concerns about the negative externalities of meat production. For cultivated meat to fully …

Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

Cellular senescence is an essential tumor suppressive mechanism that prevents the
propagation of oncogenically activated, genetically unstable, and/or damaged cells …

The recent devastating pandemic has drastically reminded humanity of the importance of
constant scientific and technological progress. A strong interdisciplinary dialogue between …

The development of new high-tech systems for screening anticancer drugs is one of the
main problems of preclinical screening. Poor correlation between preclinical in vitro and in …

A major feature of neurodegeneration is disruption of central nervous system homeostasis,
during which microglia play diverse roles. In the central nervous system, microglia serve as …

Simple Summary Aging and frailty are complex processes implicating multifactorial
mechanisms, which demand for new therapeutic strategies against their devastating effects …

3-dimensional (3D) in vitro models were developed in order to mimic the complexity of real
organ/tissue in a dish. They offer new possibilities to model biological processes in more …

The superiority of in vitro 3D cultures over conventional 2D cell cultures is well recognized
by the scientific community for its relevance in mimicking the native tissue architecture and …

Organoids recapitulate many aspects of the complex three-dimensional (3D) organization
found within native tissues and even display tissue and organ-level functionality. Traditional …