For centuries, Bombyx mori silkworm silk fibroin has been used as a high-end textile fiber.
Beyond textiles, silk fibroin has also been used as a surgical suture material for decades …

The prediction of cellular function from a genotype is a fundamental goal in biology. For
metabolism, constraint-based modelling methods systematize biochemical, genetic and …

Abstract The Protein Data Bank (PDB) is one of two archival resources for experimental data
central to biomedical research and education worldwide (the other key Primary Data Archive …

Providing an introduction to medicinal chemistry, this resource covers basic principles and
background, and describes the general tactics and strategies involved in developing an …

Forces to reckon with: Supramolecular complexes, such as the one shown, are normally
based on a combination of different interactions such as ion pairing, hydrogen bonds, and …

An introductory text that emphasizes the underlying algorithmic ideas that are driving
advances in bioinformatics. This introductory text offers a clear exposition of the algorithmic …

Background Central to protein biology is the understanding of how structural elements give
rise to observed function. The surfeit of protein structural data enables development of …

Conformer generation has important implications in cheminformatics, particularly in
computational drug discovery where the quality of conformer generation software may affect …

Advances in bioinformatics and protein modeling algorithms, in addition to the enormous
increase in experimental protein structure information, have aided in the generation of …

Structure factors are the observed experimental data from X-ray crystallographic
experiments. They are the basis of the X-ray coordinate entries and as such need to be …