[HTML][HTML] Nanocarrier-based drug combination therapy for glioblastoma
M Zhao, D van Straten, MLD Broekman, V Préat… - Theranostics, 2020 - ncbi.nlm.nih.gov
The current achievements in treating glioblastoma (GBM) patients are not sufficient because
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
Agarose-based biomaterials for advanced drug delivery
Agarose is a prominent marine polysaccharide representing reversible thermogelling
behavior, outstanding mechanical properties, high bioactivity, and switchable chemical …
behavior, outstanding mechanical properties, high bioactivity, and switchable chemical …
Ultrasound trapping and navigation of microrobots in the mouse brain vasculature
A Del Campo Fonseca, C Glück, J Droux… - Nature …, 2023 - nature.com
The intricate and delicate anatomy of the brain poses significant challenges for the treatment
of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in …
of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in …
Near infrared-activatable biomimetic nanogels enabling deep tumor drug penetration inhibit orthotopic glioblastoma
Glioblastoma multiforme (GBM) is one of the most fatal malignancies due to the existence of
blood-brain barrier (BBB) and the difficulty to maintain an effective drug accumulation in …
blood-brain barrier (BBB) and the difficulty to maintain an effective drug accumulation in …
Stimulus-responsive self-assembled prodrugs in cancer therapy
Small-molecule prodrugs have become the main toolbox to improve the unfavorable
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …
Glioblastoma: current status, emerging targets, and recent advances
Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …
population of genetically unstable and highly infiltrative cells that are resistant to …
Recent advances in nano delivery systems for blood-brain barrier (BBB) penetration and targeting of brain tumors
Gliomas constitute about 80% of brain tumors and have a meager two-year survival rate.
The treatment options available are very few because of poor prognosis and a lack of …
The treatment options available are very few because of poor prognosis and a lack of …
Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
Effective and targeted human orthotopic glioblastoma xenograft therapy via a multifunctional biomimetic nanomedicine
Glioblastoma multiforme (GBM) is a fatal central nervous system tumor without effective
treatment. Chemotherapeutic agents are mainstays in the treatment of glioblastoma …
treatment. Chemotherapeutic agents are mainstays in the treatment of glioblastoma …
Advances in the knowledge of the molecular biology of glioblastoma and its impact in patient diagnosis, stratification, and treatment
B Delgado‐Martín, MÁ Medina - Advanced Science, 2020 - Wiley Online Library
Gliomas are the most common primary brain tumors in adults. They arise in the glial tissue
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …