With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

The specific loss of midbrain dopamine neurons (mDANs) causes major motor dysfunction
in Parkinson's disease, which makes cell replacement a promising therapeutic approach …

Since more than 3 decades, schizophrenia (SZ) has been regarded as a
neurodevelopmental disorder. The neurodevelopmental hypothesis proposes that SZ is …

Recent postmortem transcriptomic studies of schizophrenia (SCZ) have shown hundreds of
differentially expressed genes. However, the extent to which these gene expression …

Schizophrenia (SCZ) is a severe psychiatric and neurodevelopmental disorder. The
pathological process of SCZ starts early during development, way before the first onset of …

L-type calcium channels (LTCCs), including the Ca v 1.2 and Ca v 1.3 LTCC subtypes, are
important regulators of calcium entry into neurons, which mediates neurotransmitter release …

Exposure to chronic and unpredictable stressors can precipitate mood-related disorders in
humans, particularly in individuals with pre-existing mental health challenges. L-type …

Schizophrenia is a debilitating neuropsychiatric disorder with heterogenous symptoms
across three key domains: positive, negative and cognitive symptoms. Current therapeutic …