[HTML][HTML] Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

[HTML][HTML] Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

[HTML][HTML] Potential therapeutic targets of quercetin, a plant flavonol, and its role in the therapy of various types of cancer through the modulation of various cell signaling …

SA Almatroodi, MA Alsahli, A Almatroudi, AK Verma… - Molecules, 2021 - mdpi.com
Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

[HTML][HTML] The power of phytochemicals combination in cancer chemoprevention

B Rizeq, I Gupta, J Ilesanmi, M AlSafran… - Journal of …, 2020 - ncbi.nlm.nih.gov
Conventional therapies for cancer treatment have posed many challenges, including toxicity,
multidrug resistance and economic expenses. In contrast, complementary alternative …

Quercetin against MCF7 and CAL51 breast cancer cell lines: apoptosis, gene expression and cytotoxicity of nano-quercetin

HA Mohammed, GM Sulaiman, SS Anwar… - …, 2021 - Taylor & Francis
Aims: To evaluate the anti breast-cancer activity, biocompatibility and toxicity of poly (d, l)-
lactic-co-glycolic acid (PLGA)-encapsulated quercetin nanoparticles (Q-PLGA-NPs) …

[HTML][HTML] Emerging impact of quercetin in the treatment of prostate cancer

S Ghafouri-Fard, FA Shabestari, S Vaezi, A Abak… - Biomedicine & …, 2021 - Elsevier
Quercetin is a flavonoid agent detected in fruits and vegetables with anti-inflammatory,
antioxidant, and anticancer effects. This flavonoid can suppress cell cycle transition and …

[HTML][HTML] Recent updates on anticancer mechanisms of polyphenols

E Sharma, DC Attri, P Sati, P Dhyani… - Frontiers in Cell and …, 2022 - frontiersin.org
In today's scenario, when cancer cases rapidly increase both in developed and developing
countries, anti-cancerous plant-based compounds become imperative. Numerous plants …

[HTML][HTML] Quercetin: a molecule of great biochemical and clinical value and its beneficial effect on diabetes and cancer

AS Michala, A Pritsa - Diseases, 2022 - mdpi.com
Quercetin belongs to the broader category of polyphenols. It is found, in particular, among
the flavonols, and along with kaempferol, myricetin and isorhamnetin, it is recognized as a …

[HTML][HTML] Combination anticancer therapies using selected phytochemicals

WH Talib, D Awajan, RA Hamed, AO Azzam… - Molecules, 2022 - mdpi.com
Cancer is still one of the most widespread diseases globally, it is considered a vital health
challenge worldwide and one of the main barriers to long life expectancy. Due to the …

Co‐administration of curcumin with other phytochemicals improves anticancer activity by regulating multiple molecular targets

N Ghobadi, A Asoodeh - Phytotherapy Research, 2023 - Wiley Online Library
Natural plant phytochemicals are effective against different types of diseases, including
cancer. Curcumin, a powerful herbal polyphenol, exerts inhibitory effects on cancer cell …