THAT the testes are related to the sexual characteristics of the individual and have
reproductive power was observed at an early time in history. One of the earliest descriptions …

Five main cell types are present in the Leydig cell lineage, namely the mesenchymal
precursor cells, progenitor cells, newly formed adult Leydig cells, immature Leydig cells, and …

Mammalian sex determination involves complex interacting networks of cellular and
hormonal signals leading to the development of male or female phenotype. Three main …

Adult Leydig cells originate within the testis postnatally. Their formation is a continuous
process involving gradual transformation of progenitors into the mature cell type. Despite the …

This review centers around studies which have used ethane dimethane sulphonate (EDS)
selectively to destroy all of the Leydig cells in the adult rat testis. With additional …

Significant differences have been observed in the rates of transmission and disease
development in human immunodeficiency virus (HIV) types 1 and 2. Because many HIV-2 …

Spermatogenesis occurs within the seminiferous tubules of the testis, in close association
with the somatic cells of the seminiferous epithelium, the Sertoli cells. At the completion of …

Leydig cells (LCs) are the cells of the testis that have as their primary function the production
of testosterone. LCs are a common target of compounds tested in rodent carcinogenicity …

Mammalian sex determination involves complex interacting networks of cellular and
hormonal signals leading to the development of male or female phenotypes. Three main …

Acrylamide (ACR) is a toxic chemical formed in foods processed at high temperature; it is a
food‐borne toxicant with increasing public health attention due to its carcinogenic …