Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

Cardiac fibrosis is a common pathophysiologic companion of most myocardial diseases,
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …

In this review we summarize the current understanding of signal transduction downstream of
vascular endothelial growth factor A (VEGFA) and its receptor VEGFR 2, and the relationship …

Intercellular communication between mesenchymal stem cells (MSC s) and their target cells
in the perivascular environment is modulated by exosomes derived from MSC s. However …

Muscle development involves a series of morphogenetic events including cell fusion,
migration and epidermal attachment. At various points in this complex developmental …

Abstract Machine learning approaches have shown great promise in biology and medicine
discovering hidden information to further understand complex biological and pathological …

The RGD-binding α5 and αv integrins have been shown to be key regulators of vascular
smooth muscle cell (vSMC) function in vitro. However, their role on vSMCs during vascular …

Acute aortic dissection (AAD) is a devastating disease with high mortality; however, the
pathogenic mechanisms of AAD remain poorly understood. Our present study aimed to …

A pathway-based genome-wide association analysis has recently identified Rac1 as one of
the biologically important gene in coronary heart diseases. The role of the small GTPase …

Pelargonidin is a natural red pigment found in fruits and vegetables, and has been reported
to exhibit various effects potentially beneficial for human health. However, the possible …