Non-stochastic generation of genetic vaccines
JM Short - US Patent 6,479,258, 2002 - Google Patents
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Exonuclease-mediated nucleic acid reassembly in directed evolution
JM Short, TD Djavakhishvili, GJ Frey - US Patent 6,361,974, 2002 - Google Patents
This invention provides methods of obtaining novel polynucleotides and encoded
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
Synthetic ligation reassembly in directed evolution
JM Short - US Patent 6,605,449, 2003 - Google Patents
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Non-stochastic generation of genetic vaccines and enzymes
JM Short - US Patent 6,713,279, 2004 - Google Patents
This invention pertains to the field of genetic vaccines. Specifically, the invention provides
multi-component genetic vaccines that contain components that are optimized for a …
multi-component genetic vaccines that contain components that are optimized for a …
End selection in directed evolution
JM Short, GJ Frey - US Patent 6,773,900, 2004 - Google Patents
This invention relates to the field of protein engineering. More specifically, this relates to a
directed evolution method for preparing a polynucleotides encoding polypeptide, which …
directed evolution method for preparing a polynucleotides encoding polypeptide, which …
Synthetic ligation reassembly in directed evolution
J Short - US Patent App. 10/422,523, 2004 - Google Patents
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Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and …
JM Short - 2002 - Google Patents
The invention is directed to methods for generating sets, or libraries, of nucleic acids
encoding antigen-binding sites, such as antibodies, antibody domains or other fragments …
encoding antigen-binding sites, such as antibodies, antibody domains or other fragments …
End selection in directed evolution
JM Short, GJ Frey - US Patent 6,740,506, 2004 - Google Patents
This invention provides methods of obtaining novel polynucleotides and encoded
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
End selection in directed evolution
JM Short, GJ Frey - US Patent 6,713,282, 2004 - Google Patents
This invention provides methods of obtaining novel polynucleotides and encoded
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
Exonuclease-mediated nucleic acid reassembly in directed evolution
JM Short - US Patent 6,635,449, 2003 - Google Patents
This invention provides methods of obtaining novel polynucleotides and encoded
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …
polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™) …