Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia
B Richter, B Hemmingsen… - Cochrane Database …, 2018 - cochranelibrary.com
Background Intermediate hyperglycaemia (IH) is characterised by one or more
measurements of elevated blood glucose concentrations, such as impaired fasting glucose …
measurements of elevated blood glucose concentrations, such as impaired fasting glucose …
Comparison of triglyceride-glucose index and HOMA-IR for predicting prevalence and incidence of metabolic syndrome
Background and aims Insulin resistance is related closely to metabolic syndrome (MetS).
The homeostasis model assessment of insulin resistance (HOMA-IR) is the most commonly …
The homeostasis model assessment of insulin resistance (HOMA-IR) is the most commonly …
Identification of type 2 diabetes loci in 433,540 East Asian individuals
Meta-analyses of genome-wide association studies (GWAS) have identified more than 240
loci that are associated with type 2 diabetes (T2D),; however, most of these loci have been …
loci that are associated with type 2 diabetes (T2D),; however, most of these loci have been …
Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores
Genome-wide association studies (GWASs) have been mostly conducted in populations of
European ancestry, which currently limits the transferability of their findings to other …
European ancestry, which currently limits the transferability of their findings to other …
The triglyceride–glucose index is a more powerful surrogate marker for predicting the prevalence and incidence of type 2 diabetes mellitus than the homeostatic …
Aims Insulin resistance is an independent risk factor for developing type 2 diabetes.
Therefore, this study compared the predictability of the triglyceride–glucose (TyG) index and …
Therefore, this study compared the predictability of the triglyceride–glucose (TyG) index and …
Genetic discrimination: introducing the Asian perspective to the debate
H Kim, CWL Ho, CH Ho, PS Athira, K Kato… - NPJ Genomic …, 2021 - nature.com
Our article aims to provide a comprehensive portrayal of how seven Asian jurisdictions have
sought to address the challenge of genetic discrimination (GD) by presenting an analysis of …
sought to address the challenge of genetic discrimination (GD) by presenting an analysis of …
The Korea Biobank Array: design and identification of coding variants associated with blood biochemical traits
S Moon, YJ Kim, S Han, MY Hwang, DM Shin… - Scientific reports, 2019 - nature.com
We introduce the design and implementation of a new array, the Korea Biobank Array
(referred to as KoreanChip), optimized for the Korean population and demonstrate findings …
(referred to as KoreanChip), optimized for the Korean population and demonstrate findings …
Prediction of type 2 diabetes using genome-wide polygenic risk score and metabolic profiles: a machine learning analysis of population-based 10-year prospective …
Background Previous work on predicting type 2 diabetes by integrating clinical and genetic
factors has mostly focused on the Western population. In this study, we use genome-wide …
factors has mostly focused on the Western population. In this study, we use genome-wide …
Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome
Metabolic syndrome (MetS) is a complex hereditary condition comprising various metabolic
traits as risk factors. Although the genetics of individual MetS components have been …
traits as risk factors. Although the genetics of individual MetS components have been …
Plant-based diets and incident metabolic syndrome: Results from a South Korean prospective cohort study
H Kim, K Lee, CM Rebholz, J Kim - PLoS medicine, 2020 - journals.plos.org
Background Prior studies have shown that plant-based diets are associated with lower risk
of cardiovascular risk factors and incident cardiovascular disease, but risks differed by …
of cardiovascular risk factors and incident cardiovascular disease, but risks differed by …