[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics

DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …

An overview of the structure and function of the flagellar hook FlgE protein

Y You, F Ye, W Mao, H Yang, J Lai, S Deng - World Journal of …, 2023 - Springer
The flagellum is an important organelle for the survival of bacteria and consists of a basal
body, hook, and filament. The FlgE protein is the subunit of the hook that connects the basal …

Identification of Antigenic Properties of Acinetobacter baumannii Proteins as Novel Putative Vaccine Candidates Using Reverse Vaccinology Approach

T Piri-Gharaghie, A Doosti, SA Mirzaei - Applied Biochemistry and …, 2022 - Springer
Multidrug-resistant Acinetobacter baumannii (A. baumannii) infections are becoming more
prevalent all over the world. As a cost-effective and preventative method, vaccination seems …

Designing of a Recombinant Multi-Epitopes Based Vaccine against Enterococcus mundtii Using Bioinformatics and Immunoinformatics Approaches

M Alharbi, A Alshammari, AF Alasmari… - International journal of …, 2022 - mdpi.com
Enterococcus species are an emerging group of bacterial pathogens that have a significant
role in hospital-associated infections and are associated with higher mortality and morbidity …

Designing a Novel Peptide-Based Multi-Epitope Vaccine to Evoke a Robust Immune Response against Pathogenic Multidrug-Resistant Providencia heimbachae

M Naveed, M Sheraz, A Amin, M Waseem, T Aziz… - Vaccines, 2022 - mdpi.com
Providencia heimbachae, a Gram-ve, rod-shaped, and opportunistic bacteria isolated from
the urine, feces, and skin of humans engage in a wide range of infectious diseases such as …

Computer-Aided Multi-Epitope Vaccine Design against Enterobacter xiangfangensis

A Alshammari, M Alharbi, A Alghamdi… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance is a global public health threat and is associated with high mortality due
to antibiotics' inability to treat bacterial infections. Enterobacter xiangfangensis is an …

Vaccinomics to design a multi-epitope-based vaccine against monkeypox virus using surface-associated proteins

S Khan, M Irfan, AR Hameed, A Ullah… - Journal of …, 2023 - Taylor & Francis
In 2022, the ongoing multi-country outbreak of monkeypox virus—now occurring outside
Africa, too is a global health concern. Monkeypox is a zoonotic virus, which causes disease …

Development of a Novel Vaccine Candidates against Cardiobacterium valvarum through Reverse Vaccinology and Computational Approaches

FF Albaqami, A Altharawi, HN Althurwi… - BioMed Research …, 2023 - Wiley Online Library
Antibiotic resistance is a major public health concern that has resulted in high healthcare
costs, increased mortality, and the emergence of novel bacterial diseases. Cardiobacterium …

Proteome-Wide Screening of Potential Vaccine Targets against Brucella melitensis

M Malik, S Khan, A Ullah, M Hassan, M Haq, S Ahmad… - Vaccines, 2023 - mdpi.com
The ongoing antibiotic-resistance crisis is becoming a global problem affecting public
health. Urgent efforts are required to design novel therapeutics against pathogenic bacterial …

In silico design of CT26 polytope and its surface display by ClearColi™-derived outer membrane vesicles as a cancer vaccine candidate against colon carcinoma

E Sharif, N Nezafat, FM Ahmadi, E Mohit - Applied Biochemistry and …, 2024 - Springer
Simultaneous targeting of several mutations can be useful in colorectal cancer (CRC) due to
its heterogeneity and presence of somatic mutations. As CT26 mutations and expression …