Neuroinflammation, stroke, blood-brain barrier dysfunction, and imaging modalities

E Candelario-Jalil, RM Dijkhuizen, T Magnus - Stroke, 2022 - Am Heart Assoc
Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …

Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives

D Li, Y Rui, S Guo, F Luan, R Liu, N Zeng - Life sciences, 2021 - Elsevier
Ferulic acid, a kind of phenolic substance widely existing in plants, is an important active
component of many traditional Chinese medicines. So far, it has been proved that ferulic …

Regulation of blood–brain barrier integrity by microglia in health and disease: a therapeutic opportunity

PT Ronaldson, TP Davis - Journal of Cerebral Blood Flow & …, 2020 - journals.sagepub.com
The blood–brain barrier (BBB) is a critical regulator of CNS homeostasis. It possesses
physical and biochemical characteristics (ie tight junction protein complexes, transporters) …

Intensive vs conventional blood pressure lowering after endovascular thrombectomy in acute ischemic stroke: the OPTIMAL-BP randomized clinical trial

HS Nam, YD Kim, JN Heo, H Lee, JW Jung, JK Choi… - Jama, 2023 - jamanetwork.com
Importance Optimal blood pressure (BP) control after successful reperfusion with
endovascular thrombectomy (EVT) for patients with acute ischemic stroke is unclear …

Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

W Abdullahi, D Tripathi… - American Journal of …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) is a physical and biochemical barrier that precisely controls
cerebral homeostasis. It also plays a central role in the regulation of blood-to-brain flux of …

Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update

AG Lee, TH Mader, CR Gibson, W Tarver, P Rabiei… - npj …, 2020 - nature.com
Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual
physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity …

Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent

JR De Oliveira, SEA Camargo… - Journal of biomedical …, 2019 - Springer
Rosmarinus officinalis L.(rosemary) is a medicinal plant native to the Mediterranean region
and cultivated around the world. Besides the therapeutic purpose, it is commonly used as a …

Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American …

EC Jauch, JL Saver, HP Adams Jr, A Bruno… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …

Hypoxia, oxidative stress, and inflammation: three faces of neurodegenerative diseases

A Merelli, M Repetto, A Lazarowski… - Journal of Alzheimer's …, 2021 - content.iospress.com
The cerebral hypoxia-ischemia can induce a wide spectrum of biologic responses that
include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and …

Barrier function in the peripheral and central nervous system—a review

AK Reinhold, HL Rittner - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
The peripheral (PNS) and central nervous system (CNS) are delicate structures, highly
sensitive to homeostatic changes—and crucial for basic vital functions. Thus, a selection of …