Epithelial–mesenchymal transition (EMT) is a complex molecular program that regulates
changes in cell morphology and function during embryogenesis and tissue development …

Hypoxia, a condition of low oxygen tension in tissues, has emerged as a crucial factor in
tumor pathophysiology. Hypoxic microenvironment gives rise to altered cellular metabolism …

Increased matrix rigidity associated with the fibrotic reaction is documented to stimulate
intracellular signalling pathways that promote cancer cell survival and tumour growth …

Transcription factors are regulatory proteins that either activate or repress the transcription of
genes via binding to DNA regulatory sequences and regulating recruitment of transcriptional …

Despite commendable progress in the prevention, detection, and treatment of a wide variety
of solid tumor types, oral squamous cell carcinoma (OSCC) remains a significant health …

The cancer stem cell (CSC) model defines tumors as hierarchically organized entities,
containing a small population of tumorigenic CSC, or tumour-initiating cells, placed at the …

Many studies have shown evidence in support of the beneficial effects of phytochemicals in
preventing chronic diseases, including cancer. Among such phytochemicals, sulphur …

Oral cancers consist of squamous cell carcinoma (SCC) and other malignancies in the
mouth with varying degrees of invasion and differentiation. For many years, different …

Epithelial–mesenchymal transition (also known as EMT) is a fundamental mechanism
occurring during embryonic development and tissue differentiation, being also crucial for …

Porphyromonas gingivalis is a host-adapted oral pathogen associated with chronic
periodontitis that successfully survives and persists in the oral epithelium. Recent studies …