The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

Inflammatory bowel disease (IBD) is a term encompassing a few chronic inflammatory
disorders that leads to damage of the intestinal tract. Although much progress has been …

Immunoglobulin A (IgA) maintains commensal communities in the intestine while preventing
dysbiosis. IgA generated against intestinal microbes assures the simultaneous binding to …

Inflammatory bowel disease (IBD), a general term encompassing Crohn's disease (CD) and
ulcerative colitis (UC), and other conditions, is a chronic and relapsing autoimmune disease …

The intestinal tract harbors diverse microorganisms, host‐and microbiota‐derived
metabolites, and potentially harmful dietary antigens. The epithelial barrier separates the …

Intrathecal IgM production in multiple sclerosis is associated with a worse disease course.
To investigate pathogenic relevance of autoreactive IgM in multiple sclerosis, CSF from two …

Thyroid cancer (TC), the most frequent malignancy of the endocrine system, has recorded
an increasing incidence in the last decades. The etiology of TC remains at least partly …

Understanding the role of the microbiome in inflammatory diseases requires the
identification of microbial effector molecules. We established an approach to link disease …

Vibrio cholerae (V. cholerae), the etiological agent of cholera, uses cholera toxin (CT) to
cause severe diarrheal disease. Cholera is still a significant cause of mortality worldwide …

The lymphatic fluid is the conduit by which part of the tissue" omics" is transported to the
draining lymph node for immunosurveillance. Following cannulation of the pre-nodal …