An aberrant STAT pathway is central to COVID-19

T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2 infection and characterized by diverse clinical
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …

Inflammation and cardiovascular disease: from pathogenesis to therapeutic target

E Golia, G Limongelli, F Natale, F Fimiani… - Current atherosclerosis …, 2014 - Springer
Atherosclerosis represents the most common pathological substrate of coronary heart
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …

Understanding the connection between common stroke comorbidities, their associated inflammation, and the course of the cerebral ischemia/reperfusion cascade

Ł Przykaza - Frontiers in immunology, 2021 - frontiersin.org
Despite the enormous progress in the understanding of the course of the ischemic stroke
over the last few decades, a therapy that effectively protects neurovascular units (NVUs) and …

Vitamin D in neurological diseases: a rationale for a pathogenic impact

R Moretti, ME Morelli, P Caruso - International journal of molecular …, 2018 - mdpi.com
It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Anti-inflammatory treatments for chronic diseases: a review

D Laveti, M Kumar, R Hemalatha… - … & Allergy-Drug …, 2013 - ingentaconnect.com
Inflammation is viewed as one of the major causes for the development of different diseases
like cancer, cardiovascular disease, diabetes, obesity, osteoporosis, rheumatoid arthritis …

Molecular regulation of contractile smooth muscle cell phenotype: implications for vascular tissue engineering

JA Beamish, P He, K Kottke-Marchant… - … Engineering Part B …, 2010 - liebertpub.com
The molecular regulation of smooth muscle cell (SMC) behavior is reviewed, with particular
emphasis on stimuli that promote the contractile phenotype. SMCs can shift reversibly along …

MicroRNAs as diagnostic and prognostic biomarkers in ischemic stroke—a comprehensive review and bioinformatic analysis

C Eyileten, Z Wicik, S De Rosa, D Mirowska-Guzel… - Cells, 2018 - mdpi.com
Stroke is the second-most common cause of death worldwide. The pathophysiology of
ischemic stroke (IS) is related to inflammation, atherosclerosis, blood coagulation, and …

Pathophysiology of acute coronary syndrome

CG Santos-Gallego, B Picatoste… - Current atherosclerosis …, 2014 - Springer
Despite improvements in interventional and pharmacological therapy for atherosclerotic
disease, it is still the leading cause of death in the developed world. Hence, there is a need …

Biomarkers for prediction of venous thromboembolism in cancer

I Pabinger, J Thaler, C Ay - Blood, The Journal of the American …, 2013 - ashpublications.org
Cancer patients are at increased risk of deep vein thrombosis and pulmonary embolism. The
incidence among different groups of cancer patients varies considerably depending on …

The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseases

M Janjusevic, G Gagno, AL Fluca, L Padoan… - Life sciences, 2022 - Elsevier
Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …