Using causal diagrams to improve the design and interpretation of medical research
Causal directed acyclic graphs (cDAGs) have become popular tools for researchers to better
examine biases related to causal questions. DAGs comprise a series of arrows connecting …
examine biases related to causal questions. DAGs comprise a series of arrows connecting …
To adjust or not to adjust: the role of different covariates in cardiovascular observational studies
Covariate adjustment is integral to the validity of observational studies assessing causal
effects. It is common practice to adjust for as many variables as possible in observational …
effects. It is common practice to adjust for as many variables as possible in observational …
The causal effect and impact of reproductive factors on breast cancer using super learner and targeted maximum likelihood estimation: a case-control study in Fars …
Objectives The relationship between reproductive factors and breast cancer (BC) risk has
been investigated in previous studies. Considering the discrepancies in the results, the aim …
been investigated in previous studies. Considering the discrepancies in the results, the aim …
Protective effect of intensive glucose lowering therapy on all-cause mortality, adjusted for treatment switching using G-estimation method, the ACCORD trial
M Shakiba, M Nazemipour, N Mansournia… - Scientific Reports, 2023 - nature.com
Previous analysis of the action to control cardiovascular risk in diabetes showed an
increased risk of mortality among patients receiving intensive glucose lowering therapy …
increased risk of mortality among patients receiving intensive glucose lowering therapy …
Sex differences in physical activity and incident stroke: a systematic review
Purpose Physical inactivity, a modifiable risk factor for cardiovascular disease, is
independently associated with stroke. Though some prior data have suggested sex …
independently associated with stroke. Though some prior data have suggested sex …
Estimating the marginal causal effect and potential impact of waterpipe smoking on risk of multiple sclerosis using the targeted maximum likelihood estimation method …
I Abdollahpour, S Nedjat… - American journal of …, 2021 - academic.oup.com
There are few if any reports regarding the role of lifetime waterpipe smoking in the etiology
of multiple sclerosis (MS). In a population-based incident case-control study conducted in …
of multiple sclerosis (MS). In a population-based incident case-control study conducted in …
The relationship of pain reduction with prevention of knee replacement under dynamic intervention strategies
SR Jafarzadeh, T Neogi, DK White… - Arthritis & …, 2022 - Wiley Online Library
Objective Knee replacement (KR) rates are increasing exponentially in the US and straining
insurance budgets. This study was undertaken to investigate how many KRs would be …
insurance budgets. This study was undertaken to investigate how many KRs would be …
[HTML][HTML] Population attributable fraction in textbooks: time to revise
Introduction The population attributable fraction is an important measure for assessing the
impact of intervention on the disease risk in populations, but it is frequently misused in the …
impact of intervention on the disease risk in populations, but it is frequently misused in the …
Methods matter: population attributable fraction (PAF) in sport and exercise medicine
A Khosravi, RO Nielsen… - British journal of sports …, 2020 - bjsm.bmj.com
Background Physical inactivity kills as many people as smoking—a newspaper heading
reads 1 following a Lancet publication 2 suggesting that more than 5 million deaths would …
reads 1 following a Lancet publication 2 suggesting that more than 5 million deaths would …
[HTML][HTML] Longitudinal effects of lipid indices on incident cardiovascular diseases adjusting for time-varying confounding using marginal structural models: 25 years …
Background This study assesses the effect of blood lipid indices and lipid ratios on
cardiovascular diseases (CVDs) using inverse probability-of-exposure weighted estimation …
cardiovascular diseases (CVDs) using inverse probability-of-exposure weighted estimation …