Using causal diagrams to improve the design and interpretation of medical research

M Etminan, GS Collins, MA Mansournia - Chest, 2020 - Elsevier
Causal directed acyclic graphs (cDAGs) have become popular tools for researchers to better
examine biases related to causal questions. DAGs comprise a series of arrows connecting …

To adjust or not to adjust: the role of different covariates in cardiovascular observational studies

M Etminan, JM Brophy, G Collins, M Nazemipour… - American Heart …, 2021 - Elsevier
Covariate adjustment is integral to the validity of observational studies assessing causal
effects. It is common practice to adjust for as many variables as possible in observational …

The causal effect and impact of reproductive factors on breast cancer using super learner and targeted maximum likelihood estimation: a case-control study in Fars …

A Almasi-Hashiani, S Nedjat, R Ghiasvand, S Safiri… - BMC Public Health, 2021 - Springer
Objectives The relationship between reproductive factors and breast cancer (BC) risk has
been investigated in previous studies. Considering the discrepancies in the results, the aim …

Protective effect of intensive glucose lowering therapy on all-cause mortality, adjusted for treatment switching using G-estimation method, the ACCORD trial

M Shakiba, M Nazemipour, N Mansournia… - Scientific Reports, 2023 - nature.com
Previous analysis of the action to control cardiovascular risk in diabetes showed an
increased risk of mortality among patients receiving intensive glucose lowering therapy …

Sex differences in physical activity and incident stroke: a systematic review

TE Madsen, M Samaei, A Pikula, YX Amy, C Carcel… - Clinical …, 2022 - Elsevier
Purpose Physical inactivity, a modifiable risk factor for cardiovascular disease, is
independently associated with stroke. Though some prior data have suggested sex …

Estimating the marginal causal effect and potential impact of waterpipe smoking on risk of multiple sclerosis using the targeted maximum likelihood estimation method …

I Abdollahpour, S Nedjat… - American journal of …, 2021 - academic.oup.com
There are few if any reports regarding the role of lifetime waterpipe smoking in the etiology
of multiple sclerosis (MS). In a population-based incident case-control study conducted in …

The relationship of pain reduction with prevention of knee replacement under dynamic intervention strategies

SR Jafarzadeh, T Neogi, DK White… - Arthritis & …, 2022 - Wiley Online Library
Objective Knee replacement (KR) rates are increasing exponentially in the US and straining
insurance budgets. This study was undertaken to investigate how many KRs would be …

[HTML][HTML] Population attributable fraction in textbooks: time to revise

A Khosravi, M Nazemipour, T Shinozaki… - Global …, 2021 - Elsevier
Introduction The population attributable fraction is an important measure for assessing the
impact of intervention on the disease risk in populations, but it is frequently misused in the …

Methods matter: population attributable fraction (PAF) in sport and exercise medicine

A Khosravi, RO Nielsen… - British journal of sports …, 2020 - bjsm.bmj.com
Background Physical inactivity kills as many people as smoking—a newspaper heading
reads 1 following a Lancet publication 2 suggesting that more than 5 million deaths would …

[HTML][HTML] Longitudinal effects of lipid indices on incident cardiovascular diseases adjusting for time-varying confounding using marginal structural models: 25 years …

F Koohi, D Khalili, H Soori, M Nazemipour… - Global …, 2022 - Elsevier
Background This study assesses the effect of blood lipid indices and lipid ratios on
cardiovascular diseases (CVDs) using inverse probability-of-exposure weighted estimation …