3D printed personalized nerve guide conduits for precision repair of peripheral nerve defects

K Liu, L Yan, R Li, Z Song, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
The treatment of peripheral nerve defects has always been one of the most challenging
clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment …

[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration

W Xue, W Shi, Y Kong, M Kuss, B Duan - Bioactive materials, 2021 - Elsevier
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

[HTML][HTML] Application of bioactive hydrogels combined with dental pulp stem cells for the repair of large gap peripheral nerve injuries

L Luo, Y He, L Jin, Y Zhang, FP Guastaldi… - Bioactive materials, 2021 - Elsevier
Due to the limitations in autogenous nerve grafting or Schwann cell transplantation, large
gap peripheral nerve injuries require a bridging strategy supported by nerve conduit. Cell …

In vitro and in vivo biocompatibility evaluation of a 3D bioprinted gelatin-sodium alginate/rat Schwann-cell scaffold

Z Wu, Q Li, S Xie, X Shan, Z Cai - Materials Science and Engineering: C, 2020 - Elsevier
Peripheral nerve injuries often cause different degrees of sensory and motor function loss.
Currently, the repair effect of the “gold standard”, autologous nerve transplantation, is …

Biocompatibility evaluation of a 3D-bioprinted alginate-GelMA-bacteria nanocellulose (BNC) scaffold laden with oriented-growth RSC96 cells

Z Wu, S Xie, Y Kang, X Shan, Q Li, Z Cai - Materials Science and …, 2021 - Elsevier
Peripheral nerve injury can cause various degrees of damage to the morphological structure
and physiological function of the peripheral nerve. At present, compared with “gold …

Functional polymer‐based nerve guide conduits to promote peripheral nerve regeneration

X Zhang, W Qu, D Li, K Shi, R Li, Y Han… - Advanced Materials …, 2020 - Wiley Online Library
Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a
challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve …

Peripheral nerve injury: current challenges, conventional treatment approaches, and new trends in biomaterials-based regenerative strategies

R López-Cebral, J Silva-Correia, RL Reis… - ACS Biomaterials …, 2017 - ACS Publications
Damage to peripheral nerves is a widely extended health problem, causing important
socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been …

Materials for peripheral nerve repair constructs: Natural proteins or synthetic polymers?

H Gregory, JB Phillips - Neurochemistry International, 2021 - Elsevier
The efficacious repair of severe peripheral nerve injuries is currently an unmet clinical need,
and biomaterial constructs offer a promising approach to help promote nerve regeneration …

Collagen and collagenolytic proteases: A review

PK Bhagwat, PB Dandge - Biocatalysis and agricultural biotechnology, 2018 - Elsevier
Despite of having enormous applications, the use of collagen is predominantly limited
because of its high cost. Most of the mammalian sources used for its production have major …

Design and fabrication of polymeric hydrogel carrier for nerve repair

X Ma, M Wang, Y Ran, Y Wu, J Wang, F Gao, Z Liu, J Xi… - Polymers, 2022 - mdpi.com
Nerve regeneration and repair still remain a huge challenge for both central nervous and
peripheral nervous system. Although some therapeutic substances, including …