Chemokines are a large family of small chemotactic cytokines that coordinates immune cell
trafficking. In cancer, they have a pivotal role in the migration pattern of immune cells into the …

Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are
27 times higher than in people. Prognosis in both species is relatively poor, with 5 year OSA …

Over 1.66 million humans (approx. 500/100 000 population rate) and over 4.2 million dogs
(approx. 5300/100 000 population rate) are diagnosed with cancer annually in the USA. The …

Cancer is a common problem in dogs and although all breeds of dog and crossbred dogs
may be affected, it is notable that some breeds of pedigree dogs appear to be at increased …

Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …

Genomic and precision medicine research has afforded notable advances in human cancer
treatment, yet applicability to other species remains uncertain. Through whole-exome and …

Despite extensive research over many decades, human breast cancer remains a major
worldwide health concern. Advances in pre-clinical and clinical research has led to …

Purpose Dogs have been proposed as spontaneous animal models of human breast
cancer, based on clinicopathologic similarities between canine and human mammary …

Considering the complexity of the current framework in oncology, the relevance of animal
models in biomedical research is critical in light of the capacity to produce valuable data with …

While cancer remains the major cause of death worldwide, nanomaterial (NM)-based
diagnosis and treatment modalities are showing remarkable potential to better tackle clinical …