The global burden of stroke remains high, and of the various subtypes of stroke, large vessel
occlusions (LVOs) account for the largest proportion of stroke-related death and disability …

Ischemic stroke is a highly complex and devastating neurological disease. The sudden loss
of blood flow to a brain region due to an ischemic insult leads to severe damage to that area …

Background and Purpose—In acute ischemic stroke patients, diffusion-weighted imaging
(DWI)–Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is correlated …

Importance Endovascular therapy (ET) is typically not considered for patients with large
baseline ischemic cores (irreversibly injured tissue). Computed tomographic perfusion …

Objective Mechanical thrombectomy (MT) is not recommended for acute stroke with large
vessel occlusion (LVO) and a large volume of irreversibly injured tissue (“core”). Perfusion …

This review summarizes the current state of knowledge regarding the use of imaging to
guide stroke treatment. Brain imaging plays a central role in the diagnosis of stroke and …

Objectives To systematically review the literature for reversible diffusion-weighted imaging
(DWIR) lesions and to describe its prevalence, predictors, and clinical significance. Methods …

Background We aimed to identify the large ischemic core (LIC) volume ranges in acute
ischemic stroke patients that can benefit from mechanical thrombectomy (MT). Methods …

Background and purpose Whether to withhold mechanical thrombectomy when the diffusion‐
weighted imaging (DWI) lesion exceeds a given volume is undetermined. Our aim was to …

Imaging has played a vital role in our mechanistic understanding of acute ischemia and the
management of acute stroke patients. The most recent DAWN and DEFUSE-3 trials showed …