Diagnosis of COVID-19 by PCR offers high sensitivity, but the utility of detecting samples
with high cycle threshold (CT) values remains controversial. Currently available rapid …

Androgens can have variable effects on men and women. Women may be evaluated for
androgen excess for several reasons. Typically, young premenopausal women present with …

Background The last few years have seen major advances in blood biomarkers for
Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising …

Background Tuberculosis (TB) infection was responsible for an estimated 1.3 million deaths
in 2017. Better diagnostic tools are urgently needed. We sought to determine whether …

BACKGROUND: Tumor markers (TMs) are a heterogeneous group of molecules used in the
diagnosis, prognosis and follow-up of cancer patients. During neoplastic differentiation, cells …

The cancer biomarker discovery pipeline is progressing slowly. The difficulties of finding
novel and effective biomarkers for diagnosis and management of cancer patients are well …

Digital PCR provides high sensitivity and unprecedented accuracy in DNA quantification, but
current approaches require dedicated instrumentation and have limited opportunities for …

Background Gliomas are aggressive malignant tumors, with poor prognosis. There is an
unmet need for the discovery of new, non-invasive biomarkers for differential diagnosis …

Background Certain demyelinating disorders, such as neuromyelitis optica spectrum
disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease …

A switch DNA template was designed to transform proteins into linear DNA strands of 97 nt.
The linear DNA was subjected to quantitative polymerase chain reaction (qPCR) to …