Semaphorins in adult nervous system plasticity and disease

D Carulli, F De Winter, J Verhaagen - Frontiers in synaptic …, 2021 - frontiersin.org
Semaphorins, originally discovered as guidance cues for developing axons, are involved in
many processes that shape the nervous system during development, from neuronal …

Development in the mammalian auditory system depends on transcription factors

KL Elliott, G Pavlínková, VV Chizhikov… - International journal of …, 2021 - mdpi.com
We review the molecular basis of several transcription factors (Eya1, Sox2), including the
three related genes coding basic helix–loop–helix (bHLH; see abbreviations) proteins …

Magnesium‐encapsulated injectable hydrogel and 3D‐engineered polycaprolactone conduit facilitate peripheral nerve regeneration

Z Yao, W Yuan, J Xu, W Tong, J Mi, PC Ho… - Advanced …, 2022 - Wiley Online Library
Peripheral nerve injury is a challenging orthopedic condition that can be treated by autograft
transplantation, a gold standard treatment in the current clinical setting. Nevertheless, limited …

gEAR: Gene Expression Analysis Resource portal for community-driven, multi-omic data exploration

J Orvis, B Gottfried, J Kancherla, RS Adkins, Y Song… - Nature …, 2021 - nature.com
To the Editor—Biologists are important stakeholders in genomic data, both as data
generators and as users of genomic data resources. Tools to efficiently visualize and …

RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy

JC Necarsulmer, JM Simon, BA Evangelista, Y Chen… - Elife, 2023 - elifesciences.org
TDP-43 proteinopathies including frontotemporal lobar degeneration (FTLD) and
amyotrophic lateral sclerosis (ALS) are neurodegenerative disorders characterized by …

[HTML][HTML] Potential neurotoxicity, immunotoxicity, and carcinogenicity induced by metribuzin and tebuconazole exposure in earthworms (Eisenia fetida) revealed by …

G Li, D Li, H Rao, X Liu - Science of The Total Environment, 2022 - Elsevier
Metribuzin and tebuconazole have been widely used in agriculture for several decades.
Apart from endocrine disruption, little is known about their toxicological effects on organisms …

[HTML][HTML] Remote ischemic preconditioning causes transient cell cycle arrest and renal protection by a NF-κB–dependent Sema5B pathway

J Rossaint, M Meersch, K Thomas, S Mersmann… - JCI insight, 2022 - ncbi.nlm.nih.gov
Acute kidney injury increases morbidity and mortality, and previous studies have shown that
remote ischemic preconditioning (RIPC) reduces the risk of acute kidney injury after cardiac …

High‐throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory‐deprived cortical cholinergic VIP/CHAT neurons

N Yayon, O Amsalem, T Zorbaz, O Yakov… - The EMBO …, 2023 - embopress.org
Cortical neuronal networks control cognitive output, but their composition and modulation
remain elusive. Here, we studied the morphological and transcriptional diversity of cortical …

Single-Cell RNA Analysis of Type I Spiral Ganglion Neurons Reveals a Lmx1a Population in the Cochlea

FC Grandi, L De Tomasi, M Mustapha - Frontiers in molecular …, 2020 - frontiersin.org
In the mature cochlea, each inner hair cell (IHC) is innervated by multiple spiral ganglion
neurons of type I (SGNI). SGNIs are morphologically and electro-physiologically diverse …

[HTML][HTML] Subtype maturation of spiral ganglion neurons

S Sun, C Siebald, U Müller - … opinion in otolaryngology & head and …, 2021 - journals.lww.com
The recent molecular studies open new avenues to rigorously test whether SGN subtypes
are important for the encoding of different sound features and if they show differential …