How to perform and interpret provocative testing for the diagnosis of Brugada syndrome, long-QT syndrome, and catecholaminergic polymorphic ventricular …

MN Obeyesekere, GJ Klein, S Modi… - Circulation …, 2011 - Am Heart Assoc
Sudden cardiac death (SCD) is predominantly related to coronary artery disease and its
sequelae, cardiomyopathy, and congenital or valvular heart disease. No structural …

Diagnosis and clinical management of long-QT syndrome

C Steinberg - Current Opinion in Cardiology, 2018 - journals.lww.com
This review outlines our current understanding and approach to the clinical diagnosis and
management of LQT as well as recent insights into genotype–phenotype correlations …

Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands

RW Sy, C van der Werf, IS Chattha, P Chockalingam… - Circulation, 2011 - Am Heart Assoc
Background—Genetic testing can diagnose long-QT syndrome (LQTS) in asymptomatic
relatives of patients with an identified mutation; however, it is costly and subject to …

The diagnostic utility of recovery phase QTc during treadmill exercise stress testing in the evaluation of long QT syndrome

JM Horner, MM Horner, MJ Ackerman - Heart Rhythm, 2011 - Elsevier
BACKGROUND: Nearly 40% of patients with long QT syndrome (LQTS) can have a
nondiagnostic QTc at rest. Treadmill and cycle exercise stress testing are used in the …

Epinephrine infusion in the evaluation of unexplained cardiac arrest and familial sudden death: from the cardiac arrest survivors with preserved Ejection Fraction …

AD Krahn, JS Healey, VS Chauhan… - Circulation …, 2012 - Am Heart Assoc
Background—Epinephrine infusion may unmask latent genetic conditions associated with
cardiac arrest, including long-QT syndrome and catecholaminergic polymorphic ventricular …

Effect of beta-blockers on QT dynamics in the long QT syndrome: measuring the benefit

MT Bennett, LJ Gula, GJ Klein, AC Skanes, R Yee… - Europace, 2014 - academic.oup.com
Aims Beta-blockers are the standard of care for the treatment of long QT syndrome (LQTS),
and have been shown to reduce recurrent syncope and mortality in patients with type 1 …

Characterization of myocardial repolarization reserve in adolescent females with anorexia nervosa

GJ Padfield, CA Escudero, AM DeSouza, C Steinberg… - Circulation, 2016 - Am Heart Assoc
Background—Patients with anorexia nervosa exhibit abnormal myocardial repolarization
and are susceptible to sudden cardiac death. Exercise testing is useful in unmasking QT …

Prolonged QT interval in athletes: Distinguishing between pathology and physiology

GA Christou, AP Vlahos, KA Christou, S Mantzoukas… - Cardiology, 2022 - karger.com
Background: The physiological QT prolongation in athletes is expected to widen the gray
zone between physiology and pathology of QT, increasing the diagnostic challenges …

The influence of exercise and postural changes on ventricular repolarization in the long QT syndrome: a systematic scoping review

A Harvey, D Curnier, P Dodin, S Abadir… - European Journal of …, 2022 - academic.oup.com
Current exercise recommendations make it difficult for long QT syndrome (LQTS) patients to
adopt a physically active and/or athletic lifestyle. The purpose of this review is to summarize …

[HTML][HTML] Exercise test for patients with long QT syndrome

CH Chan, YF Hu, PF Chen, IC Wu… - Acta Cardiologica …, 2022 - ncbi.nlm.nih.gov
Congenital long QT syndrome (LQTS) causes life-threatening cardiac arrhythmias and is the
leading cause of sudden cardiac death in young people. Measurements of QT prolongation …