[HTML][HTML] May phytophenolics alleviate aflatoxins-induced health challenges? A holistic insight on current landscape and future prospects

H Rasouli, FD Nayeri, R Khodarahmi - Frontiers in nutrition, 2022 - frontiersin.org
The future GCC-connected environmental risk factors expedited the progression of nCDs.
Indeed, the emergence of AFs is becoming a global food security concern. AFs are lethal …

[HTML][HTML] In vitro and in vivo assessment of AFB1 and OTA toxic effects and the beneficial role of bioactive compounds. A systematic review

M Frangiamone, Á Lázaro, A Cimbalo, G Font… - Food Chemistry, 2024 - Elsevier
The purpose of this review was to investigate the current knowledge about aflatoxin B1
(AFB1) and ochratoxin A (OTA) toxicity and the possible beneficial role of bioactive …

[HTML][HTML] Arabic Gum Could Alleviate the Aflatoxin B1-provoked Hepatic Injury in Rat: The Involvement of Oxidative Stress, Inflammatory, and Apoptotic Pathways

N Ahmed, SM El-Rayes, WF Khalil, A Abdeen… - Toxins, 2022 - mdpi.com
Aflatoxin B1 (AF) is an unavoidable environmental pollutant that contaminates food, feed,
and grains, which seriously threatens human and animal health. Arabic gum (AG) has …

[HTML][HTML] Dietary aflatoxin B1 and antimalarial—a lumefantrine/artesunate—therapy perturbs male rat reproductive function via pro-inflammatory and oxidative …

SE Owumi, AO Umez, U Arunsi, CE Irozuru - Scientific Reports, 2023 - nature.com
We investigated the impact of Coartem™(COA) and aflatoxin B1 (AFB1) on rats'
hypothalamus, epididymis, and testis. Male rats were randomly grouped (n= 5 rats) and …

Chlorogenic acid, rutin, and quercetin from Lysimachia christinae alleviate triptolide-induced multi-organ injury in vivo by modulating immunity and AKT/mTOR signal …

X Wu, J Wang, B Li, M Gong, C Cao, L Song… - Toxicology and Applied …, 2023 - Elsevier
Drug-induced organ injury is one of the key factors causing organ failure and death in the
global public. Triptolide (TP) is the main immunosuppressive component of Tripterygium …

[HTML][HTML] Nephroprotective effects of Acacia Senegal against aflatoxicosis via targeting inflammatory and apoptotic signaling pathways

O Shanab, SM El-Rayes, WF Khalil, N Ahmed… - Ecotoxicology and …, 2023 - Elsevier
Abstract Aflatoxin B 1 (AFB1) is a common environmental pollutant that poses a major
hazard to both humans and animals. Acacia senegal (Gum) is well-known for having …

Apigeninidin-enriched Sorghum bicolor (L. Moench) extracts alleviate Aflatoxin B1-induced dysregulation of male rat hypothalamic-reproductive axis

SE Owumi, MT Otunla, UO Arunsi… - … Biology and Medicine, 2022 - journals.sagepub.com
We examined the protective effect of the apigeninidin (API)-enriched fraction from Sorghum
bicolor sheaths extracts (SBE-05, SBE-06, and SBE-07) against aflatoxin B1 (AFB1)-induced …

The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats

SE Owumi, UO Arunsi… - Fundamental & Clinical …, 2023 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is known to derange the hepatorenal system by redox, DNA
adduct formation and apoptotic networks. Endogenous 3‐indole propionic acid (3‐IPA) is a …

Dietary chamomile flowers extract improved performance and mitigated aflatoxin B1 toxicity in rabbits

MG Rashad, MM Arafa, AEI El‐Zanaty… - Journal of Animal …, 2024 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is among the poisonous mycotoxins that contaminate food and
feed. Limited studies are available on the efficacy of chamomile (Cha) against oxidative …

[HTML][HTML] Auricularia auricular Adsorbs Aflatoxin B1 and Ameliorates Aflatoxin B1-Induced Liver Damage in Sprague Dawley Rats

D Xu, M Huang, J Lei, H Song, L Hu, H Mo - Foods, 2023 - mdpi.com
Aflatoxin B1 (AFB1), as a class I carcinogen, poses a substantial health risk to individuals.
Contamination of food sources, particularly grains and nuts, with Aspergillus flavus (A …