Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease caused by
deletion or mutation of SMN1. Four subtypes exist, characterized by different clinical …

Objective Multiple sclerosis (MS) is associated with cognitive impairment (CI) such as
slowed information processing speed (IPS). Currently, no immunocellular or molecular …

Within the neurovascular unit (NVU), the blood–brain barrier (BBB) operates as a key
cerebrovascular interface, dynamically insulating the brain parenchyma from peripheral …

In patients with Parkinson's disease (PD), constipation is common, and it appears in a
prodromal stage before the hallmark motor symptoms. The present study aimed to …

Abstract Purpose of Review Autologous haematopoietic stem cell transplantation (AHSCT)
is increasingly considered a treatment option for patients with multiple sclerosis (MS), an …

Developing effective disease-modifying therapies for neurodegenerative diseases (NDs)
requires reliable diagnostic, disease activity, and progression indicators. While desirable …

Vitamin E is often associated with health benefits, such as antioxidant, anti-inflammatory and
cholesterol-lowering effects. These properties make its supplementation a suitable …

Toxic protein aggregates can spread among neurons to promote human neurodegenerative
disease pathology. We found that in C. elegans touch neurons intermediate filament …

The urgent need for new therapies for some devastating neuromuscular diseases (NMDs),
such as Duchenne muscular dystrophy or amyotrophic lateral sclerosis, has led to an …

Neurofilaments are structural proteins found in the cytoplasm of neurons, particularly in
axons, providing structural support and stability to the axon. They consist of multiple …