Lost in transcription: p21 repression, mechanisms, and consequences
AL Gartel, SK Radhakrishnan - Cancer research, 2005 - AACR
The cyclin-dependent kinase inhibitor p21WAF1/CIP1 is a major player in cell cycle control
and it is mainly regulated at the transcriptional level. Whereas induction of p21 …
and it is mainly regulated at the transcriptional level. Whereas induction of p21 …
[HTML][HTML] Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections
Chronic infections with hepatitis B (HBV) and hepatitis C viruses (HCV) are the leading
cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide. Both viruses encode …
cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide. Both viruses encode …
Epigenetic Silencing of the PTEN Gene in Melanoma
A Mirmohammadsadegh, A Marini, S Nambiar… - Cancer research, 2006 - AACR
Phosphatase and tensin homologue deleted from chromosome 10 (PTEN) seems to be an
important tumor suppressor gene in melanoma. Because the PTEN gene is only infrequently …
important tumor suppressor gene in melanoma. Because the PTEN gene is only infrequently …
Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2
D Selimovic, M Hassan, Y Haikel, UR Hengge - Cellular Signalling, 2008 - Elsevier
Taxol (paclitaxel) is a new antineoplastic drug that has shown promise in the treatment of
different tumor types. However, the molecular mechanisms governing taxol-induced …
different tumor types. However, the molecular mechanisms governing taxol-induced …
Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway …
K Machida, G McNamara, KTH Cheng… - The Journal of …, 2010 - journals.aai.org
Hepatitis C virus (HCV) infection is associated with the development of hepatocellular
carcinoma and putatively also non-Hodgkin's B cell lymphoma. In this study, we …
carcinoma and putatively also non-Hodgkin's B cell lymphoma. In this study, we …
[PDF][PDF] Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways
Chronic hepatitis C virus (HCV) infection is associated with the production of serum
cytokines, including transforming growth factor (TGF)‐β2. Despite the occurrence of hepatic …
cytokines, including transforming growth factor (TGF)‐β2. Despite the occurrence of hepatic …
Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b
P Arora, EO Kim, JK Jung, KL Jang - Cancer letters, 2008 - Elsevier
E-cadherin is a major cell adhesion molecule implicated as a potent tumor suppressor,
which is frequently altered in human tumors including hepatocellular carcinoma. Here, we …
which is frequently altered in human tumors including hepatocellular carcinoma. Here, we …
[HTML][HTML] Significance of hepatitis virus infection in the oncogenic initiation of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death
worldwide. Chronic infection of hepatitis B virus (HBV) and/or hepatitis C virus (HCV) is a …
worldwide. Chronic infection of hepatitis B virus (HBV) and/or hepatitis C virus (HCV) is a …
[HTML][HTML] Hepatitis B-and hepatitis C-related hepatocellular carcinomas in the United States: similarities and differences
J Ng, J Wu - Hepatitis monthly, 2012 - ncbi.nlm.nih.gov
Hepatitis B- and Hepatitis C-Related Hepatocellular Carcinomas in the United States:
Similarities and Differences - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
Similarities and Differences - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
Hepatitis C virus and cellular stress response: implications to molecular pathogenesis of liver diseases
PY Ke, SSL Chen - Viruses, 2012 - mdpi.com
Infection with hepatitis C virus (HCV) is a leading risk factor for chronic liver disease
progression, including steatosis, cirrhosis, and hepatocellular carcinoma. With …
progression, including steatosis, cirrhosis, and hepatocellular carcinoma. With …