Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine …

M Bekhbat, Z Li, ND Mehta, MT Treadway… - Molecular …, 2022 - nature.com
Increased inflammation in major depressive disorder (MDD) has been associated with low
functional connectivity (FC) in corticostriatal reward circuits and symptoms of anhedonia …

Reward-related predictors of symptom change in behavioral activation therapy for anhedonic adolescents: a multimodal approach

CA Webb, L Murray, AO Tierney, EE Forbes… - …, 2023 - nature.com
Anhedonia is a cardinal characteristic of depression which predicts worse treatment
outcome and is among the most common residual symptoms following treatment. Behavioral …

Lateral hypothalamus orexinergic projection to the medial prefrontal cortex modulates chronic stress-induced anhedonia but not anxiety and despair

D Liu, X Zheng, Y Hui, Y Xu, J Du, Z Du, Y Che… - Translational …, 2024 - nature.com
Chronic stress-induced anxiodepression is a common health problem, however its potential
neurocircuitry mechanism remains unclear. We used behavioral, patch-clamp …

Dynamic processes in behavioral activation therapy for anhedonic adolescents: Modeling common and patient-specific relations.

CA Webb, L Murray, AO Tierney… - Journal of Consulting and …, 2023 - psycnet.apa.org
Objective: Behavioral activation (BA) is a brief intervention for depression encouraging
gradual and systematic re-engagement with rewarding activities and behaviors. Given this …

Spontaneous thought characteristics are differentially related to heightened negative affect versus blunted positive affect in adolescents: An experience sampling …

CA Webb, AO Tierney, HA Brown, EE Forbes… - JCPP …, 2022 - Wiley Online Library
Background Mind‐wandering has been linked to negative affect (NA) and depressive
symptoms in adolescents. However, mind‐wandering is an extremely broad and …