Breast cancer (BC) is the second most common cancer and the fifth deadliest in the world.
Exposure to endocrine disrupting pollutants has been suggested to contribute to the …

The aryl hydrocarbon receptor (AhR) is a ligand-activated basic-helix-loop-helix
transcription factor that binds structurally diverse ligands and senses cues from …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …

Published in 1980: In a previous publication on glucuronic acid both free and conjugated,
the author expressed the hope that glucuronic acid studies over the following few years …

Mice and guinea pigs were given a single oral dose of various chlorinated dibenzo-p-
dioxins (CDD) to establish and compare the LD50 and clinical and pathologic …

Only the small group of the polychlorinated polycyclic compounds given in Figures 1 and 2
will be reviewed in this article. Several years ago when this laboratory was the Atlanta …

In 1977 the International Agency for Research on Cancer (IARC) first reviewed the evidence
of TCDD carcinogenicity in humans and other animals (1, 2). The group decided that TCDD …

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TC-DD) is one of the most toxic compounds known.
TCDD and other chlorinated dibenzodioxins have been associated with occupational …

Rats were given 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) at dosages of 0, 0.001, 0.01,
0.1, or 1.0 μg/kg, 5 days/wk for 13 wk. Doses of 1.0 μg TCDD/kg/day caused some mortality …