With the aging of the world's population, a large proportion of patients seen in
cardiovascular practice are older adults, but many patients also exhibit signs of physical …

Normal circulatory function is a key determinant of disease-free life expectancy (healthspan).
Indeed, pathologies affecting the cardiovascular system, which are growing in prevalence …

Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Frailty is an important factor determining a higher risk of adverse health outcomes in older
adults. Although scientific community in the last two decades put a lot of effort for its …

The pathogenesis of frailty and the role of inflammation is poorly understood. We examined
the evidence considering the relationship between inflammation and frailty through a …

Chronic inflammation is associated with normal and pathological ageing. Here we show that
chronic, progressive low-grade inflammation induced by knockout of the nfkb1 subunit of the …

Background The ability of acute care providers to cope with the influx of frail older patients is
increasingly stressed, and changes need to be made to improve care provided to older …

Aims The aim of this study was to evaluate the prevalence, clinical features, and the
independent impact of frailty—a geriatric syndrome characterized by the decline of …

The term “frailty” is used to describe a subset of older adults who appear weaker and more
vulnerable than their age-matched counterparts, despite having similar comorbidities …

Background: Frailty is an important risk factor for cardiovascular disease (CVD), but the
impact of early, potentially reversible stages of frailty on CVD risk is unknown. Objectives …