Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

The process of programmed cell death, or apoptosis, is generally characterized by distinct
morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is …

Macroautophagy is a dynamic process involving the rearrangement of subcellular
membranes to sequester cytoplasm and organelles for delivery to the lysosome or vacuole …

Apoptosis is a primary characteristic in the pathogenesis of liver disease. Hepatic apoptosis
is regulated by autophagic activity. However, mechanisms mediating their interaction remain …

Apoptotic cell death is usually a response to the cell's microenvironment. In the kidney,
apoptosis contributes to parenchymal cell loss in the course of acute and chronic renal …

N-Methyl-D-aspartate (NMDA) receptor-mediated neurotoxicity may depend, in part, on the
generation of nitric oxide (NO.) and superoxide anion (O2.-), which react to form peroxynitrite …

Defects in cell-death pathways are hallmarks of cancer. Although resistance to apoptosis is
closely linked to tumorigenesis, tumour cells can still be induced to die by non-apoptotic …

The mechanisms underlying neoplastic epithelial cell killing by ionizing radiation are largely
unknown. We discovered a novel response to radiation manifested by autophagy and the …

PURPOSE: To investigate whether retinal ganglion cell death in experimental glaucoma and
after axotomy occurs by apoptosis. METHODS: Chronic elevated eye pressure was …

The term cell necrobiology is introduced to comprise the life processes associated with
morphological, biochemical, and molecular changes which predispose, precede, and …