Recent advances on CDK inhibitors: An insight by means of in silico methods
M Tutone, AM Almerico - European Journal of Medicinal Chemistry, 2017 - Elsevier
The cyclin dependent kinases (CDKs) are a small family of serine/threonine protein kinases
that can act as a potential therapeutic target in several proliferative diseases, including …
that can act as a potential therapeutic target in several proliferative diseases, including …
In silico approaches in carcinogenicity hazard assessment: current status and future needs
RR Tice, A Bassan, A Amberg, LT Anger… - Computational …, 2021 - Elsevier
Historically, identifying carcinogens has relied primarily on tumor studies in rodents, which
require enormous resources in both money and time. In silico models have been developed …
require enormous resources in both money and time. In silico models have been developed …
دراسة العلاقة الكمية بين الفاعلية والصيغة البنائية باستخدام طريقتي (MLR وPC-ANN) لبعض المركبات التي لها فعالية على بروتين Translocator (TSPO
هناء سليم حسين بني عودة - 2016 - dspace.alquds.edu
Quantitative structure-activity relationship study was performed to understand the activity of a
set of 136 ligands of Translocator protein (TSPO) compounds. QSAR models were …
set of 136 ligands of Translocator protein (TSPO) compounds. QSAR models were …
Protein kinases: Structure modeling, inhibition, and protein-protein interactions
KM Elokely - 2013 - egrove.olemiss.edu
Human protein kinases belong to a large and diverse enzyme family that contains more than
500 members. Deregulation of protein kinases is associated with many disorders, and this is …
500 members. Deregulation of protein kinases is associated with many disorders, and this is …