The developmental origins of health and disease hypothesis applied to neurodevelopmental
outcomes asserts that the fetal origins of future development are relevant to mental health …

The early environment has a major impact on the developing embryo, fetus, and infant.
Parental adversity (maternal and paternal) and glucocorticoid exposure before conception …

Maternal stress can prenatally influence offspring phenotypes and there are an increasing
number of ecological studies that are bringing to bear biomedical findings to natural …

It has been approximately 30 years since the seminal discoveries of David Barker and his
colleagues, and research is beginning to unravel the mechanisms that underlie …

Background Maternal childhood maltreatment (MCM) is linked to poor perinatal outcomes
but the evidence base lacks cohesion. We explore the impact of MCM on four perinatal …

Pre-natal exposure to acute maternal trauma or chronic maternal distress can confer
increased risk for psychiatric disorders in later life. Acute maternal trauma is the result of …

Parental exposure to stress or glucocorticoids either before or during pregnancy can have
profound influences on neurodevelopment, neuroendocrine function and behaviours in …

Understanding if and how individuals and populations cope with environmental change is
an enduring question in evolutionary ecology that has renewed importance given the pace …

Hypothalamic–pituitary–adrenal axis (HPA) flexibility is an emerging concept recognizing
that individuals that will cope best with stressors will probably be those using their hormones …

There is growing evidence that the environment experienced by one generation can
influence phenotypes in the next generation via transgenerational plasticity (TGP). One of …