COVID-19-associated opportunistic infections: a snapshot on the current reports

A Abdoli, S Falahi, A Kenarkoohi - Clinical and experimental medicine, 2022 - Springer
Abstract Treatment of the novel Coronavirus Disease 2019 (COVID-19) remains a
complicated challenge, especially among patients with severe disease. In recent studies …

Coccidioidomycosis: a contemporary review

NF Crum - Infectious diseases and therapy, 2022 - Springer
Coccidioidomycosis, colloquially known as Valley Fever, is an invasive dimorphic fungal
infection caused by Coccidioides immitis and C. posadasii. The fungi are found in the arid …

Results from a national survey on COVID‐19‐associated mucormycosis in Germany: 13 patients from six tertiary hospitals

D Seidel, M Simon, R Sprute, M Lubnow, K Evert… - Mycoses, 2022 - Wiley Online Library
Background Most COVID‐19‐associated mucormycosis (CAM) cases are reported from
India and neighbouring countries. Anecdotally cases from Europe have been presented …

Repurposing and optimization of drugs for discovery of novel antifungals

MJ Donlin, MJ Meyers - Drug discovery today, 2022 - Elsevier
Highlights•There is a dire need for novel antifungal therapies.•Recent clinical trials of directly
repurposed drugs have failed.•The most recently approved antifungals underwent …

COVID-19-associated fungal infections in Iran: A systematic review

T Nazari, F Sadeghi, A Izadi, S Sameni, S Mahmoudi - PLoS One, 2022 - journals.plos.org
Objectives This systematic review aims to summarize the mycological and clinical features of
COVID-19-associated fungal infections (CAFIs) in Iran. Methods PubMed, Web of Science …

Discovery of pyrazolone carbothioamide derivatives as inhibitors of the Pdr1-KIX interaction for combinational treatment of azole-resistant candidiasis

Q Wang, J Tu, W Yang, T Liang, N Liu… - Journal of Medicinal …, 2023 - ACS Publications
Candida glabrata has emerged as an important opportunistic pathogen of invasive
candidiasis due to increasing drug resistance. Targeting Pdr1-KIX interactions with small …

Fungal colonization and infections—interactions with other human diseases

SS Mahalingam, S Jayaraman, P Pandiyan - Pathogens, 2022 - mdpi.com
Candida albicans is a commensal fungus that asymptomatically colonizes the skin and
mucosa of 60% of healthy individuals. Breaches in the cutaneous and mucosal barriers …

Discovery of a new chemical scaffold for the treatment of superbug Candida auris infections

J Tu, T Zhu, Q Wang, W Yang, Y Huang… - Emerging Microbes & …, 2023 - Taylor & Francis
Candida auris has emerged as a serious threat of public health and caused global epidemic
due to multi-drug resistance, remarkable transmissibility and high mortality. To tackle the …

Current landscape of coccidioidomycosis

R Boro, PC Iyer, MA Walczak - Journal of Fungi, 2022 - mdpi.com
Coccidioidomycosis, also known as Valley fever, is an endemic fungal infection commonly
found in the southwestern parts of the United States. However, the disease has seen an …

Synthesis and bacteriostatic properties of epoxybenzooxocino [4, 3-b] pyridine derivatives

AL Stalinskaya, NV Martynenko, LE Alkhimova… - Journal of Molecular …, 2023 - Elsevier
We report a successful chemical modification of (2, 5-dimethyl-11, 12-dihydro-5H-5, 11-
epoxybenzo [7, 8] oxocino [4, 3-b] pyridin-3-yl) ethan-1-one at C-3 position. The main …