Metformin for cardiovascular protection, inflammatory bowel disease, osteoporosis, periodontitis, polycystic ovarian syndrome, neurodegeneration, cancer …
M Ala, M Ala - ACS pharmacology & translational science, 2021 - ACS Publications
Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …
Hyperandrogenism and Polycystic ovary syndrome: Effects in pregnancy and offspring development
GA Abruzzese, AF Silva, ME Velazquez… - WIREs mechanisms …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is one of the major endocrine disorders affecting women
of reproductive age. Its etiology remains unclear. It is suggested that environmental factors …
of reproductive age. Its etiology remains unclear. It is suggested that environmental factors …
Insight into TLR4 receptor inhibitory activity via QSAR for the treatment of Mycoplasma pneumonia disease
Mycoplasma pneumoniae (MP) is one of the most common pathogenic organisms causing
upper and lower respiratory tract infections, lung injury, and even death in young children …
upper and lower respiratory tract infections, lung injury, and even death in young children …
Systemic and ovarian inflammation in women with polycystic ovary syndrome
Y Zhai, Y Pang - Journal of Reproductive Immunology, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is a common endocrine/reproductive/metabolic disorder.
The etiology of PCOS is complex and has been linked to low-grade chronic inflammation …
The etiology of PCOS is complex and has been linked to low-grade chronic inflammation …
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome‐Induced Pyroptosis via Inhibiting the TLR4/NF‐κB/PFKFB3 Signaling in …
Y Zhang, W Liu, Y Zhong, Q Li, M Wu… - Oxidative Medicine …, 2021 - Wiley Online Library
NOD‐like receptor family, pyrin domain‐containing protein 3 (NLRP3) inflammasome‐
mediated pyroptosis is a crucial event in the preeclamptic pathogenesis, tightly linked with …
mediated pyroptosis is a crucial event in the preeclamptic pathogenesis, tightly linked with …
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome
M Hu, Y Zhang, S Ma, J Li, X Wang… - Molecular human …, 2021 - academic.oup.com
The mechanisms that link hyperandrogenism and insulin (INS) resistance (HAIR) to the
increased miscarriage rate in women with polycystic ovary syndrome (PCOS) remain …
increased miscarriage rate in women with polycystic ovary syndrome (PCOS) remain …
The abnormal level of HSP70 is related to Treg/Th17 imbalance in PCOS patients
Y Yang, J Xia, Z Yang, G Wu, J Yang - Journal of Ovarian Research, 2021 - Springer
Background Polycystic ovary syndrome (PCOS) is a disease with chronic nonspecific low-
grade inflammation. The imbalance of immune cells exists in PCOS. Several studies have …
grade inflammation. The imbalance of immune cells exists in PCOS. Several studies have …
Transcriptomic screening to identify hub genes and drug signatures for PCOS based on RNA-Seq data in granulosa cells
M Zanjirband, M Baharlooie, Z Safaeinejad… - Computers in Biology …, 2023 - Elsevier
Background Polycystic ovary syndrome (PCOS) is one of the most incident reproductive
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …
Dysregulation of immune response in PCOS organ system
J Wang, T Yin, S Liu - Frontiers in immunology, 2023 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder
affecting women, which can lead to infertility. Infertility, obesity, hirsutism, acne, and irregular …
affecting women, which can lead to infertility. Infertility, obesity, hirsutism, acne, and irregular …
Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin …
Y Zhang, M Hu, F Yang, Y Zhang, S Ma… - Journal of Molecular …, 2021 - Springer
In this study, we show that during normal rat pregnancy, there is a gestational stage-
dependent decrease in androgen receptor (AR) abundance in the gravid uterus and that this …
dependent decrease in androgen receptor (AR) abundance in the gravid uterus and that this …