Despite significant reductions in morbidity and mortality secondary to availability of effective
combination anti‐retroviral therapy (cART), human immunodeficiency virus (HIV) infection …

The innate immune system has a role not only in protecting the host during the initial period
of virus infection, but also in shaping the nature of the adaptive immune response. In this …

The virological and immunological features of hepatitis C virus (HCV) infection were studied
weekly for 6 months after accidental needlestick exposure in five health care workers, four of …

To define the early events that determine the outcome of acute hepatitis C virus (HCV)
infection, we compared the course of viremia with the peripheral and intrahepatic T cell …

Background End-stage cirrhosis related to hepatitis C virus (HCV) is a common reason for
liver transplantation, although viremia is known to persist in most cases. We investigated the …

In acute hepatitis C virus (HCV) infection only 20-50% of patients spontaneously clear the
virus. To characterise the immune reaction during that phase we studied the response of …

The anti-viral T cell response is believed to play a central role in the pathogenesis of
hepatitis C virus infection. Since chronic evolution occurs in> 50% of HCV infections, the …

Hepatitis C virus (HCV) is an important human pathogen that is remarkably efficient at
establishing persistent infection. The HCV core protein is the first protein expressed during …

One striking clinical feature of hepatitis C virus (HCV) infection is that more than 50% of
patients with acute hepatitis C will develop chronic infection. To investigate its possible …

We investigated the infection of peripheral blood mononuclear cells (PBMNC) by hepatitis C
virus (HCV) in 5 patients with HCV-related chronic hepatitis. The presence of HCV-RNA …